七氟醚复合不同剂量异丙酚麻醉对颅脑手术患者颅内压及脑灌注压的影响  

Effect of Different doses of Sevoflurane Combined with Propofol on Intracranial Pressure and Perfusion Pressure in Patients Undergoing Craniocerebral Surgery

作　　者：范清丽 FAN Qingli(Panjin Central Hospital of Liaoning Province,Panjin 124000,China)

机构地区：[1]辽宁省盘锦市中心医院,辽宁盘锦124000

出　　处：《中国医药指南》2021年第3期99-100,共2页Guide of China Medicine

摘　　要：目的分析七氟醚复合不同剂量异丙酚麻醉对颅脑手术患者颅内压及脑灌注压的变化情况。方法2018年1月至2019年1月在本院接受颅脑手术治疗的患者中随机挑选44例,将其分为对比组和观察组(n=22),比较两组患者麻醉前后颅内压、脑灌注压的变化情况及麻醉效果。结果相比于对比组,观察组患者ICP、MAP数值在持续麻醉5 min后得到明显降低(P<0.05);两组患者的CPP值无明显差异(P>0.05)。观察组麻醉效率高于对照组(P<0.05)。结论颅脑手术患者在手术过程中采用复合大剂量异丙酚相比于复合小剂量异丙酚,其麻醉效果更好。Objective To analyze the changes of intracranial pressure and cerebral perfusion pressure in patients undergoing craniocerebral surgery under anesthesia with different doses of propofol.Methods From January 2018 to January 2019,44 patients were randomly selected from the patients undergoing craniocerebral surgery in our hospital,and they were divided into a comparison group and an observation group(n=22).The changes of intracranial pressure and cerebral perfusion pressure and the effect of anesthesia were compared between the two groups of patients before and after anesthesia.Results Compared with the control group,the ICP and MAP values of the observation group were significantly reduced after 5 minutes of continuous anesthesia(P<0.05);there was no significant difference in CPP values between the two groups(P>0.05).The anesthesia efficiency of the observation group was higher than that of the control group(P<0.05).Conclusion Patients undergoing craniocerebral surgery in our hospital are anesthetized with sevoflurane combined with different doses of propofol,and the anesthetic effect of high dose propofol is better than that of low dose propofol.

关 键 词：颅脑手术 七氟醚 异丙酚 不同剂量 颅内压 脑灌注压 麻醉效果 

分 类 号：R614[医药卫生—麻醉学] R651.15[医药卫生—外科学]