定量血流分数临床研究进展及应用  

Clinical research progress and application of quantitative flow ratio

作　　者：陈聪 赵洋[1] 张魁[1] 董然[1] Chen Cong;Zhao Yang;Zhang Kui;Dong Ran(Department of Cardiac Surgery,Beijing Anzhen Hospital,Capital Medical University,Beijing 100029,China)

机构地区：[1]首都医科大学附属北京安贞医院心外科,100029

出　　处：《中华胸心血管外科杂志》2021年第1期59-62,共4页Chinese Journal of Thoracic and Cardiovascular Surgery

基　　金：北京市科学技术委员会-首都临床特色应用研究与成果推广(Z171100001017059)。

摘　　要：准确评估冠状动脉狭窄程度在指导冠心病血运重建方面十分重要。近年来,基于功能学评估冠状动脉狭窄对于远端心肌的影响正改变着传统血运重建的理念。血流储备分数指导冠状动脉介入治疗的优势已被临床验证,但因其操作有创、费用较高、检查中应用血管扩张药物副作用较大等原因,在我国应用相对受限。定量血流分数作为一种新型、无创、快速评估冠状动脉功能学狭窄程度的工具,受到研究者的青睐。本文综述定量血流分数的临床研究进展,并展望其未来临床应用。Accurate assessment of the degree of coronary artery stenosis is very important to guide the revascularization of patients with coronary heart disease.In recent years,functional assessment of the impact of coronary artery stenosis on the distal myocardium is changing the traditional concept of revascularization.The superiority of the fractional flow reserve(FFR)in guiding coronary interventional therapy has been widely verified in clinical practice.Due to its invasive operation,high cost,and high side effects of vasodilators during examinations,its application in my country is relatively limited.Quantitative flow ratio as a new,noninvasive,and rapid tool for assessing coronary stenosis,is being favored by researchers.This article reviews the clinical research progress of quantitative flow ratio and prospects its future clinical applications.

关 键 词：临床研究进展 血流储备分数 冠状动脉介入治疗 血管扩张药物 血运重建 狭窄程度 临床验证 冠状动脉狭窄 

分 类 号：R541.4[医药卫生—心血管疾病]