基于便携式扫描仪与智能手机的尿酸定量检测技术  

Detection Technology of Uric Acid with a Portable Scanner and Smartphone

作　　者：侯鹏飞 张校亮 谭慷 李晓春 HOU Pengfei;ZHANG Xiaoliang;TAN Kang;LI Xiaochun(College of Physics and Optoelectronics,Key Laboratory of Advanced Transducers and Intelligent Control System Ministry of Education and Shanxi Province,Taiyuan University of Technology,Taiyuan 030024,China;College of Biomedical Engineering,Taiyuan University of Technology,Taiyuan 030024,China)

机构地区：[1]太原理工大学物理与光电工程学院,新型传感器与智能控制教育部与山西省重点实验室,太原030024 [2]太原理工大学生物医学工程学院,太原030024

出　　处：《太原理工大学学报》2021年第2期307-312,共6页Journal of Taiyuan University of Technology

基　　金：国家自然科学基金资助项目(21874098,81741095,61775157);山西省重点研发计划(国际科技合作)资助项目(201903D421053);山西省应用基础研究面上青年基金资助项目(201801D221194)。

摘　　要：尿酸检测对人体健康状况实时监测具有重要意义。研究开发了一种基于便携式扫描仪结合智能手机的尿酸定量检测方法,并设计及制作了适用于该检测方法的滤纸芯片,可以实现对人体血清中尿酸的定量检测,具有便携、快速、检测结果准确的优点。此方法检测限为0.8 mg/dL,并且对实际样品的检测结果与紫外分光光度计测量的结果一致。检测过程无需复杂的操作流程及昂贵仪器的辅助,可应用于医疗设备匮乏的乡镇地区、普通用户家中以及现场快速定量检测,具有广泛的市场应用前景。Detection of uric acid is crucial for real-time monitoring of human health.In this work,a method of portable scanner-based quantitative detection of uric acid with a smartphone was developed,meanwhile,a filter paper chip was designed and fabricated for the detection process,which provides an on-site,fast,and accurate measurement of the uric acid in human blood serum.The limit of detection was 0.8 mg/dL,and the detection results of human serum samples showed good agreement between the spectrophotometric method and the proposed one.This method does not require complex operations or expensive instruments,which is suitable for resource-limited areas,users’home,as well as on-site detection,with wide applications and broad market prospects.

关 键 词：便携式扫描仪 智能手机 滤纸芯片 尿酸 定量检测 

分 类 号：TP274[自动化与计算机技术—检测技术与自动化装置]