经咽鼓管途径鼓室内灌注给药对突发性耳聋的挽救治疗观察  

Observation on the Salvage Treatment of Sudden Deafness Treated by Intratympanic Infusion via Eustachian Tube

作　　者：漆可[1] 曹春婷[1] QI Ke;CAO Chun-ting

机构地区：[1]北京市普仁医院耳鼻咽喉科,北京100062

出　　处：《中国听力语言康复科学杂志》2021年第2期146-148,共3页Chinese Scientific Journal of Hearing and Speech Rehabilitation

摘　　要：目的探讨联合经咽鼓管途径鼓室内灌注给药对突发性耳聋挽救治疗的疗效。方法将已接受初始治疗无效的突聋患者81例随机分为联合组和药物组,均予以前列地尔、舒血宁和腺苷钴胺治疗,联合组在药物基础上加用经咽鼓管途径鼓室内灌注给药。结果联合组的总有效率为48.83%(20/43);平均PTA提高(19.18±10.23)dB,与常规组比较差异有统计学意义(t=2.146,P<0.05);治疗效果与关系密切,2~4周组的有效率58.62%明显优于>4周组21.42%(χ2=4.134,P<0.05)。结论联合经咽鼓管途径鼓室内灌注给药有效、安全、操作方便,且越早开始效果越好。Objective To investigate the curative effect of combined therapy with Intratympanic infusion via eustachian tube in the treatment of sudden sensorineural hearing loss(SSNHL).Methods 81 cases of sudden deafness patients who had received initial treatment were randomly divided into the combined treatment group and the drug treatment group.Both groups were given alprostadil,ginkgo biloba leaf extract and adenosine cobalt amine.On this basis,the combined treatment group was given dexamethasone by intramural perfusion via eustachian tube for 4 times.Results The total effective rate of hearing improvement in the combined treatment group was 48.83%(20/43);the average PTA increased(19.18±10.23)dB,which was statistically significant compared with the drug treatment group(t=2.146,P<0.05).In addition,the salvage treatment effect was closely related to the onset time of treatmnet.The effective rate of 58.62%in the 2-4-week group was significantly better than that of 21.42%in the>4-week group(χ2=4.134,P<0.05).Results Combined with intratympanic infusion via the eustachian tube is effective,safe and easy to operate which can be used the earlier the better.

关 键 词：鼓室内灌注 挽救性治疗 突发性感音神经性聋 咽鼓管 

分 类 号：R764.437[医药卫生—耳鼻咽喉科]