有创机械通气序贯高流量氧疗对抢救重症呼吸衰竭患者的临床效果分析  

Objective to explore the clinical effect of invasive mechanical ventilation sequential high flow oxygen therapy in the rescue of patients with severe respiratory failure

作　　者：何琼 王建民 张佳 杨花 王玉巧[1] He Qiong;Wang Jianmin;Zhang Jia;Yang Hua;Wang Yuqiao(Ningxia Hui Autonomous Region,People's Hospital,Yinchuan Ningxia 750001,China)

机构地区：[1]宁夏回族自治区人民医院,宁夏银川750001

出　　处：《医药前沿》2020年第32期10-11,共2页Journal of Frontiers of Medicine

基　　金：宁夏回族自治区卫生厅重点科研计划项目(项目编号:2019-NW-018);宁夏回族自治区人民医院培育振兴项目(项目编号:201918);宁夏自然科学基金(项目编号:2019AAC03304)。

摘　　要：目的:分析临床抢救重症呼吸衰竭患者采用有创机械通气序贯高流量氧疗法的效果。方法:选取2019年1月—2020年1月我院ICU 150例重症呼吸衰竭机械通气患者,其中63例行有创机械通气序贯高流量氧疗患者为研究组,另外87例行普通氧疗,结果:两组接受序贯治疗后,研究组的心率、二氧化碳分压指标小于对照组,呼吸频率、氧合指数等指标高于对照组,差异有统计学意义(P<0.05);研究组与参照组ICU住院时间、48h再插管率和28日死亡率相比,组间差异不显著(P>0.05)。结论:有创机械通气序贯高流量氧疗法在帮助重症呼吸衰竭患者撤机后改善患者呼吸循环等方面有较确切的效果,在ICU重症呼吸衰竭临床抢救中效果显著。Objective To study the effect of sequential high flow oxygen therapy with invasive mechanical ventilation in the treatment of severe respiratory failure.Methods from January 2019 to January 2020,150 patients with severe respiratory failure were enrolled in the ICU of our hospital.Among them,63 cases were treated with invasive mechanical ventilation followed by high flow oxygen therapy as the study group,and 87 cases were treated with ordinary oxygen therapy,Respiratory rate,oxygenation index and other indicators were higher than the control group,the difference was statistically significant(P<0.05);the ICU hospitalization time,48h re intubation rate and 28 day mortality rate of the study group and the reference group had little difference(P>0.05).Conclusion sequential high flow oxygen therapy with invasive mechanical ventilation has a definite effect on improving the respiratory and circulatory function of patients with severe respiratory failure after weaning from ventilator,which has significant value in the clinical rescue of severe respiratory failure in ICU.

关 键 词：有创机械通气 高流量氧疗 重症呼吸衰竭 ICU 治疗效果 

分 类 号：R563.8[医药卫生—呼吸系统]