达夫反应法合成2,4,6-三羟基苯-1,3,5-三甲醛反应条件研究  

Studies on Reaction Conditions for the Synthesis of Triformylphloroglucinol by Duff Reaction

作　　者：云观 刘全菊 张可鑫 蒋舰 YUN Guan;LIU Quan-ju;ZHANG Ke-xin;JIANG Jian(College of Chemistry and Chemical Engineering,Mudanjiang Normal University,Mudanjiang 157000,China)

机构地区：[1]牡丹江师范学院化学化工学院,黑龙江牡丹江157000

出　　处：《长春师范大学学报》2021年第2期95-98,共4页Journal of Changchun Normal University

基　　金：黑龙江省教育厅备案项目“新型超分子自组装离子液晶研究”(1352MSYYB010)。

摘　　要：2,4,6-三羟基苯-1,3,5-三甲醛是合成共价有机框架材料和超分子结构的重要中间体,在合成中有很多应用。经达夫反应合成2,4,6-三羟基苯-1,3,5-三甲醛具有操作简单、产物易分离等优点。本文通过对酸性介质、反应温度、反应时间、水解试剂等因素对目标化合物产率的影响,确定了合成2,4,6-三羟基苯-1,3,5-三甲醛的最佳反应条件。Triformylphloroglucinol is an important intermediate in the synthesis of covalent organic framework materials and supramolecular structures.The synthesis of triformylphloroglucinol with Duff reaction methods has the advantages of simple operation and easy separation.The optimum reaction conditions for synthesis of triformylphloroglucinol were studied.The effects of acidic medium,reaction temperature,reaction time and other factors on the yield of the target compound were discussed in this paper.

关 键 词：2 4 6-三羟基苯-1 3 5-三甲醛 达夫反应 间苯三酚 六次甲基四胺 三氟乙酸 

分 类 号：O625.41[理学—有机化学]