上尿路结石合并肾积液感染并发尿脓毒血症的危险因素分析  

Analysis of risk factors for urosepsis in patients with upper urinary calculi and renal effusion infection

作　　者：李荣均 苏劲强 欧红运 冯少林 邱旻文 张汉钊 LI Rongjun;SU Jinqiang;OU Hongyun;FENG Shaolin;QIU Minwen;ZHANG Hanzhao(Department of Urology Surgery,the People’s Hospital of Qingxin District of Qingyuan City,Guangdong Qingyuan 511800,China)

机构地区：[1]清远市清新区人民医院泌尿外科,广东清远511800

出　　处：《上海医药》2021年第5期41-44,共4页Shanghai Medical & Pharmaceutical Journal

基　　金：广东省清远市科技计划项目(190915114569542)。

摘　　要：目的 :分析上尿路结石合并肾积液感染并发尿脓毒血症的危险因素。方法 :300例上尿路结石合并肾积液感染患者的临床资料,将患者分为并发尿脓毒血症组(n=50)和未并发尿脓毒血症组(n=250例)进行组间比较,再采用多因素logistics回归分析探讨合并尿脓毒血症的危险因素。结果:单因素分析结果显示,两组在年龄、尿白细胞(WBC)或亚硝酸盐(NIT)(+)、尿培养(+)、合并糖尿病、梗阻性肾功能不全等方面比较的差异有统计学意义(P <0.05);两组女性患者间在年龄、尿WBC或NIT(+)、尿培养(+)方面比较的差异有统计学意义(P <0.05)。多因素logistic回归分析显示,年龄≥40岁、女性、尿WBC或NIT(+)、尿培养(+)、合并糖尿病、梗阻性肾功能不全是上尿路结石合并肾积液感染并发尿脓毒血症的危险因素。结论 :临床应关注这些危险因素,以便正确诊断并对症治疗。Objective:To analyze the risk factors for urosepsis in patients with upper urinary tract calculi and renal effusion infection.Methods:The clinical data from 300 patients with upper urinary tract calculi and renal effusion infection were retrospectively analyzed and they were divided into urosepsis group(n=50)and non-urosepsis group(n=250).The differences of clinical data between the two groups were compared.Multiple logistic regression analysis was used to explore the risk factors of urosepsis.Results:Univariate analysis showed that there were significant differences between the two groups in the aspects including age,urine white blood cell(WBC)or nitrite(NIT)(+),urine culture(+),diabetes mellitus and obstructive renal insufficiency(P<0.05),and there were statistically significant differences between the female patients in the age,urine WBC or NIT(+),urine culture(+)(P<0.05).Multivariate logistic regression analysis showed that age≥40 years,female,urine WBC or NIT(+),urine culture(+),diabetes mellitus and obstructive renal insufficiency were the risk factors of urinary sepsis.Conclusion:Greats attention should be paid to these risk factors in clinic so as to correctively diagnose and give symptomatic treatment.

关 键 词：上尿路结石 肾积液感染 尿脓毒血症 危险因素 

分 类 号：R692.2[医药卫生—泌尿科学] R691.4[医药卫生—外科学]