HPLC-MS/MS-LIQ法同时定性定量测定染料产品中的分散黄3  

Simultaneous qualitative and quantitative determination of Disperse Yellow 3 in dyes by HPLC-MS/MS-LIQ method

作　　者：阮瑜迪 叶琼 沈国炎 杨清清 王芬 RUAN Yudi;YE Qiong;SHEN Guoyan;YANG Qingqing;WANG Fen(Shaoxing Testing Institute of Quality and Technical Supervision,Shaoxing 312366,China;Zhejiang Supor Pharmaceuticals Co.,Ltd.,Shaoxing 312000,China)

机构地区：[1]绍兴市质量技术监督检测院,浙江绍兴312366 [2]浙江苏泊尔制药有限公司,浙江绍兴312000

出　　处：《印染》2021年第3期69-73,共5页China Dyeing and Finishing

摘　　要：采用高效液相色谱-三重四极杆/复合线性离子阱质谱,在多反应监测触发增强子离子扫描模式下对染料产品中的分散黄3同时进行定性定量测定。通过二级质谱进行定性,多反应监测扫描进行定量,定量方法检出限低于5μg/L,在20~200μg/L质量浓度范围内线性关系良好,R~2达0.998;10、50、100μg/L低中高三个质量浓度的加标回收率在90%~110%,具有较好的准确度;RSD为5.2%,具有较好的精密度。A method for simultaneous qualitative and quantitative determination of Disperse Yellow 3 in dyestuff products by high performance liquid chromatography triple quadrupole/composite linear ion trap mass spectrometry under multiple reaction monitoring trigger enhancer ion scanning mode is estab⁃lished.Qualitative analysis is carried out by secondary mass spectrometry,and quantitative analysis is carried out by multi reaction monitoring.The linear range is good in 20-200μg/L with R 2 of 0.998;the re⁃covery rate of standard addition of 10,50,100μg/L are in the range of 90%-110%,showing good accura⁃cy;RSD of 5.2%indicates the method has good precision.

关 键 词：测试 高效液相色谱-三重四极杆/复合线性离子阱质谱 二级质谱 分散黄3 

分 类 号：TS197[轻工技术与工程—纺织化学与染整工程]