5160例育龄女性孕前优生TORCH感染现状及其相关影响因素分析  

Analysis on the status and related influencing factors of TORCH infection in 5160 women of childbearing age before pregnancy

作　　者：龙诗芬 夏伟兰 季新梅 梁秀文 LONG Shi-fen;XIA Wei-lan;JI Xin-mei;LIANG Xiu-wen(Gynecology Department of Maternity Center of Longhua District People′s Hospital,Shenzhen,Guangdong 518109)

机构地区：[1]深圳市龙华区人民医院妇产中心妇科,广东深圳518109

出　　处：《中国优生与遗传杂志》2020年第12期1470-1472,1554,共4页Chinese Journal of Birth Health & Heredity

摘　　要：目的了解深圳市龙华区育龄女性孕前优生TORCH感染现状,并探讨其相关影响因素,为预防TORCH感染和提高优生优育提供参考依据。方法收集2018年3月-2020年7月在深圳市龙华区人民医院妇产中心就诊并进行孕前优生TORCH筛查的育龄女性5160例,分别采用酶联免疫吸附法(ELISA)检测风疹病毒IgG(RV-IgG)、巨细胞病毒IgM和IgG(CMV-IgM、IgG),弓形虫IgM和IgG(TOX-IgM、IgG),并对检测结果及相关影响因素进行统计分析。结果育龄女性孕前TORCH筛查中RV-IgG、CMV-IgG及TOX-IgG分别检出4632、4527及314例,阳性率分别为89.76%、87.73%和6.09%,其中以RV-IgG检出率最高;CMV-IgM和TOX-IgM分别检出65和39例,阳性率分别为1.26%和0.76%,其中以CMV-IgM检出率最高,不同TORCH-IgG和IgM阳性率之间差异有统计学意义(P<0.05);TORCH-IgG阳性率随着年龄的增大而升高,不同年龄段阳性率之间差异有统计学意义(P<0.05),而TORCH-IgM阳性率不同年龄段之间差异无统计学意义(P>0.05),养宠物和大学及以上学历育龄女性的TORCH-IgG和IgM阳性率均明显高于非养宠物和大学以下学历者,差异均有统计学意义(P<0.05);养宠物和高学历是育龄女性孕前TORCH-IgG和IgM感染的高危因素,年龄是TORCH-IgG感染的高危因素(P<0.05),而与TORCH-IgM感染无关(P>0.05)。结论深圳龙华区育龄女性孕前TORCH感染有较高的阳性率,以RV-IgG和CMV-IgM感染较为突出。因此,加强优生优育知识教育,并全面开展育龄女性孕前优生TORCH筛查工作,对优生优育和提高人口素质具有重要意义。Objective:To understand the current status of eugenic TORCH infection among women of childbearing age in Longhua District,Shenzhen city before pregnancy,and explore its related influencing factors,so as to provide reference basis for prevention of TORCH infection and improvement of eugenic and eugenic care.Methods:5160 cases of women of childbearing age who visited the gynecology and Obstetrics Center of Longhua District People′s Hospital of Shenzhen from March 2018 to July 2020 and underwent pre-pregnancy eugenic TORCH screening were collected.respectively,by using enzyme-linked immunosorbent(ELISA)to detect rubella virus IgG(RV-IgG),cytomegalovirus IgM and IgG(CMV-IgM,CMV-IgG),toxoplasma IgG and IgM(TOX-IgM,TOX-IgG),and the testing results and the related influencing factors were analyzed.Results:In TORCH screening of women of childbearing age before pregnancy,4632,4527 and 314 cases of RV-IgG,CMV-IgG and Tox-IgG were detected respectively,the positive rates were 89.76%,87.73%and 6.09%,respectively,among which the highest detection rate was RV-IgG.65 and 39 cases of CMV-IgM and Tox-IgM were detected,respectively,the positive rates of CMV-IgM and Tox-IgM were 1.26%and 0.76%,respectively,and the detection rate of CMV-IgM was the highest.The positive rate of TORCH-IgG increased with the increase of age,and the difference between different age groups was statistically significant(P<0.05),while there was no significant difference in the positive rate of TORCH-IgM between different age groups(P>0.05).Keep a pet and university or above major in women of childbearing age of the TORCH-IgG and IgM positive rate were significantly higher than that of not keep a pet and university degrees below,differences were statistically significant(P<0.05).Pet ownership and high education level are the high risk factors for TORCH IgG and IgM infection in women of childbearing age before pregnancy,and age is the high risk factor for TORCH IgG infection(P<0.05),but not related to TORCH IgM infection(P>0.05).Conclusion:TORCH infection

关 键 词：育龄女性 孕前 TORCH感染 现状 影响因素 

分 类 号：R714.5[医药卫生—妇产科学]