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作 者:王凡强 曲婧 李世浩 吴红丽 张辉 WANG Fan-qiang;QU Jing;LI Shi-hao;WU Hong-li;ZHANG Hui(Department of Laboratory Medicine,Maternity and Child Care Center of Qinhuangdao)
机构地区:[1]秦皇岛市妇幼保健院检验科,河北秦皇岛066000
出 处:《中国优生与遗传杂志》2020年第11期1342-1344,共3页Chinese Journal of Birth Health & Heredity
基 金:秦皇岛市科研立项:高敏免疫发光仪在传染八项检测的应用及秦皇岛市流行趋势调查研究。
摘 要:目的了解秦皇岛市建卡孕产妇传染四项检测结果,对孕产妇的传染病防治和管理,促进优生优育起到积极作用。方法采用希森美康HISCL-5000高敏免疫发光仪定量检测传染四项,收集2018~2019年秦皇岛市建卡孕产妇传染四项的检测结果,分析乙型肝炎表面抗原(HBsAg)、抗丙型肝炎病毒(HCV)抗体、抗梅毒螺旋体(TP)抗体的阳性率和人类免疫缺陷病毒(HIV)抗体感染情况。结果孕产妇乙型肝炎阳性率为1.6%,丙型肝炎阳性率0.13%,梅毒特异性抗体阳性率为0.26%,艾滋病抗体阳性3例经CDC复检确诊1例感染病例。各年龄段孕妇乙型肝炎表面抗原(HBsAg)阳性率有差异(P<0.05),抗丙型肝炎病毒(HCV)抗体阳性率、抗梅毒螺旋体(TP)各年龄组之间无统计学意义(P>0.05)。结论对孕产妇传染病标志物进行产前筛查有助于了解孕妇相关疾病的患病情况,及时进行母婴阻断和临床治疗,对促进优生优育有着重要的意义。Objective:Understand the results of four tests of infectious diseases among pregnant women with card establishment in Qinhuangdao City,so as to play a positive role in the prevention and management of infectious diseases and the promotion of eugenics.Method:Four items of infection were detected by Sysmex HISCL-5000 high-sensitivity immunoluminescence instrument,and the results of four items of infection in pregnant women with card establishment in Qinhuangdao city from 2018 to 2019 were collected.The positive rates of hepatitis B surface antigen(HBsAg),anti hepatitis C virus(HCV)antibody,anti Treponema pallidum(TP)antibody and human immunodeficiency virus(HIV)antibody infection were analyzed.Results:Among these pregnant women,the positive rate of hepatitis B was 1.6%,the positive rate of hepatitis C was 0.13%,the positive rate of syphilis specific antibody was 0.26%,3 cases were positive of AIDS antibody,and 1 case of infection was confirmed by CDC re-examination.The positive rate of hepatitis B surface antigen(HBsAg)was different among different age groups of pregnant women(P<0.05),the positive rate of anti HCV antibody and anti Treponema pallidum(TP)had no statistical significance(P>0.05).Conclusion:Prenatal screening of maternal infectious disease markers is helpful to understand the prevalence of related diseases of pregnant women,timely maternal and infant blocking and clinical treatment are of great significance to promote eugenics and good breeding.
关 键 词:希森美康HISCL-5000 孕产妇 乙型肝炎表面抗原(HBsAg) 抗丙型肝炎病毒(HCV)抗体 抗人类免疫缺陷病毒(HIV)抗体 抗梅毒螺旋体(TP)抗体 优生优育
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