2016-2019年湖北省流感疫情及病原学监测分析  

Epidemiology and etiology of influenza in Hubei province,2016–2019

作　　者：刘琳琳[1] 韩诗 余晓[1] 李翔[1] 叶国军[1] 方斌[1] Liu Linlin;Han Shi;Yu Xiao;Li Xiang;Ye Guojun;Fang Bin(Institute of Health Inspection and Testing,Hubei Provincial Center for Disease Control and Prevention,Wuhan 430079,Hubei,China)

机构地区：[1]湖北省疾病预防控制中心卫生检验检测研究所流感参比实验室,湖北武汉430079

出　　处：《疾病监测》2020年第12期1105-1109,共5页Disease Surveillance

基　　金：湖北省自然科学基金(No.2017CFB709)。

摘　　要：目的了解2016—2019年度湖北省流感病毒流行特征,为制定流感防控政策和风险评估提供实验室依据。方法结合流感网络监测实验室的病原学监测及流行病学调查结果,对湖北省流感监测数据开展流行病学分析。结果2016—2019年度湖北省流感样病例(ILI)占门急诊病例总数百分比(ILI%)平均为2.90,其中0~5岁年龄组人群在ILI%中所占比重最大(61.83%),60岁以上年龄组人群所占比重最低(3.69%);3个年度哨点监测标本平均阳性率为14.06%,共分离出4991份毒株,对其中565份毒株进行抗原性分析;新甲型H1N1、季节性甲型H3N2亚型和乙型Victoria系随季节(时间)呈现明显的交替现象;期间共报告343起ILI暴发疫情,疫情报告时间分布主要为每年的冬春季。结论2016—2019年度湖北省流感病毒的流行规律呈现冬春季高流行峰,夏季低流行峰,各型别交替流行,冬春季易暴发疫情。Objective To understand the epidemiologic and etiologic characteristics of influenza in Hubei province from2016 to 2019 and provide laboratory evidence for the prevention and control policy development and risk assessment of influenza in Hubei.Methods Combined with the results of etiologic surveillance and epidemiologic investigation of influenza network surveillance laboratory,the epidemiological analysis of influenza surveillance data in Hubei was carried out.Results The average proportion of influenza like illness(ILI)cases in Hubei during 2016–2019 was 2.90%.The ILI proportion was highest in 0–5-year-old group(61.83%),and lowest in people over 60 years old(3.69%).The average influenza virus positive rate in the annual sentinel surveillance during 2016–2019 was 14.06%.A total of 4991 strains of influenza viruses were isolated,and antigenic analysis was conducted for 565 strains.Influenza A(H1N1)pdm09 virus,seasonal influenza A(H3N2)virus and influenza B virus Victoria lineage circulated alternatively with seasons.During this period,a total of 343 outbreaks of ILI,mainly in winter and spring,were reported.Conclusion The annual circulation of influenza viruses showed peak in winter and spring,and sub-peak in summer in Hubei during 2016–2019,Different type influenza viruses circulated alternatively.Influenza epidemic is prone to occur in winter and spring.

关 键 词：流感样病例 哨点监测 病原学监测 防控 

分 类 号：R211[医药卫生—中医学] R511.7