Effects of Outdoor Temperature on Blood Pressure in a Prospective Cohort of Northwest China  

作　　者：ZHENG Shan WANG Min Zhen CHENG Zhi Yuan KANG Feng NIE Yong Hong MI Xiu Ying LI Hai Yan JIN Lan ZHANG Ya Wei BAI Ya Na 

机构地区：[1]Institute of Epidemiology and Statistics,School of Public Health,Lanzhou University,Lanzhou 73000,Gansu,China [2]Department of Epidemiology,School of Public Health,Brown University,Providence,Rhode Island 02903,USA [3]Workers'Hospital of Jinchuan Group Co.,Ltd.,Jinchang 737103,Gansu,China [4]Jinchang Center for Disease Prevention and Control,Jinchang 737100,Gansu,China [5]Jinchang Meteorological Service,Jinchang737100,Gansu,China [6]Department of Surgery,Yale School of Medicine,New Haven 06511,USA [7]Department of Environmental Health Sciences,Yale School of Public Health,New Haven 06511,US

出　　处：《Biomedical and Environmental Sciences》2021年第2期89-100,共12页生物医学与环境科学（英文版）

基　　金：supported by the National Science Foundation of China Grant Number 41505095, 41705122,81673248;the Fundamental Research Funds for the Central Universities in China Grant Number lzujbky-2018-69,lzujbky-2018-66。

摘　　要：Objective The relationship between outdoor temperature and blood pressure(BP) has been inconclusive. We analyzed data from a prospective cohort study in northwestern China to investigate the effect of outdoor temperature on BP and effect modification by season.Methods A total of 32,710 individuals who participated in both the baseline survey and the first follow-up in 2011–2015 were included in the study. A linear mixed-effect model and generalized additive mixed model(GAMM) were applied to estimate the association between outdoor temperature and BP after adjusting for confounding variables.Results The mean differences in systolic blood pressure(SBP) and diastolic blood pressure(DBP)between summer and winter were 3.5 mm Hg and 2.75 mm Hg, respectively. After adjusting for individual characteristics, meteorological factors and air pollutants, a significant increase in SBP and DBP was observed for lag 06 day and lag 04 day, a 0.28 mm Hg(95% CI: 0.27–0.30) per 1 °C decrease in average temperature for SBP and a 0.16 mm Hg(95% CI: 0.15–0.17) per 1 °C decrease in average temperature for DBP, respectively. The effects of the average temperature on both SBP and DBP were stronger in summer than in other seasons. The effects of the average temperature on BP were also greater if individuals were older, male, overweight or obese, a smoker or drinker, or had cardiovascular diseases(CVDs), hypertension, and diabetes.Conclusions This study demonstrated a significant negative association between outdoor temperature and BP in a high-altitude environment of northwest China. Moreover, BP showed a significant seasonal variation. The association between BP and temperature differed by season and individuals' demographic characteristics(age, gender, BMI), unhealthy behaviors(smoking and alcohol consumption), and chronic disease status(CVDs, hypertension, and diabetes).

关 键 词：Outdoor temperature SEASON Blood pressure Jinchang cohort 

分 类 号：R544[医药卫生—心血管疾病]