真空紫外光电离质谱技术进展及其在快速分析中的应用  

Progress of Vacuum Ultraviolet Photon Ionization Mass Spectrometry and Its Application in On-line Analysis

作　　者：刘兵 董丰硕 刘瑞东 侯可勇 LIU Bing;DONG Feng-shuo;LIU Rui-dong;HOU Ke-yong(Environment Research Institute,Shandong University,Qingdao 266237,China)

机构地区：[1]山东大学,环境研究院,山东青岛266237

出　　处：《分析测试学报》2021年第2期208-214,共7页Journal of Instrumental Analysis

基　　金：国家自然科学基面上项目(21675155,21874134);山东省青年泰山学者资助(tsqn201909039)。

摘　　要：真空紫外光电离源(VUV-PI)是一种普适性的质谱软电离源,真空紫外光电离质谱谱图无碎片、易解析、灵敏度高,适合于在线快速分析。真空紫外光电离质谱根据分析对象不同可以直接采用单光子电离或添加掺杂剂实现化学电离,能实现气、液、固体分析,也可实现成像分析。该文介绍了真空紫外光电离源的电离原理、光源类型,分析了光电离质谱灵敏度的影响因素及其技术改进措施,并阐述了真空紫外光电离质谱技术在环境污染物、化工产物在线分析、国家安全分析以及生物医学分析中的相关应用研究。最后,总结了真空紫外光电离源的优缺点,并对真空紫外光电离技术在性能和应用方面的发展前景进行了展望。Vacuum ultraviolet photo ionization(VUV-PI)is a universal soft ionization source for mass spectrometry(MS).The VUV-PI-MS is quite suitable for on-line rapid analysis as its mass spectrum is free of fragment ion interference,easy to be interpreted and high sensitive.According to different analytes,VUV-PI could be used in single photon ionization mode or chemical ionization mode achieved by dopant,which could be used for gas,liquid and solid sample analysis,as well as for imaging analysis.The ionization principle of the VUV-PI and the current type of vacuum ultraviolet light source are firstly introduced in this article,then the factors affecting the sensitivity of photo ionization MS and its technical improvement measures are analyzed,and finally,the applications of VUV-PI-MS technology in environmental analysis,chemical products on-line analysis,national safety analysis and related application research in biomedical analysis are also presented.In the conclusion,the advantages and disadvantages of VUV-PI are summarized,and the perspectives on developments of performance and applications of VUV-PI technique are looked forward to.

关 键 词：真空紫外光电离(VUV-PI) 真空紫外灯 软电离 在线质谱 挥发性有机物 

分 类 号：O657.63[理学—分析化学] O625.3[理学—化学]