电感耦合等离子体质谱结合红外光谱与X射线光谱的蒙药磁石质量控制方法研究  

Study on a Quality Control Method for Mongolian Medicine Magnetite Based on Inductively Coupled Plasma Mass Spectrometry Combined with Infrared Spectroscopy and X-ray Diffraction

作　　者：甄晓宇 郑重[2] 皮子凤[2] 刘舒[2] 刘志强[2] 闫静[1] ZHEN Xiao-yu;ZHENG Zhong;PI Zi-feng;LIU Shu;LIU Zhi-qiang;YAN Jing(School of Pharmacy,Heilongjiang University of Chinese Medicine,Harbin 150040,China;Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022,China)

机构地区：[1]黑龙江中医药大学药学院,黑龙江哈尔滨150040 [2]中国科学院长春应用化学研究所,吉林长春130022

出　　处：《分析测试学报》2021年第1期112-118,共7页Journal of Instrumental Analysis

基　　金：国家重点研发计划项目(2018YFC1708202);内蒙古自治区科技重大专项资金项目(2019ZD004);中国科学院信息化专项(XXH-13514-0217)。

摘　　要：通过不同方法探究蒙药磁石的物质组成并对其进行元素含量分析。采用傅里叶变换红外光谱法(FTIR)和X射线衍射法(XRD)对不同厂家的10批次磁石样品进行指纹图谱测定;采用电感耦合等离子体质谱(ICP-MS)测定磁石所含的元素,进一步确定蒙药磁石的物质组成。结果表明,红外光谱中共有7个特征峰,468 cm-1、526 cm-1处分别为石英与四氧化三铁的特征吸收峰;XRD实验确定了9个特征峰,认定磁石指纹谱中5、7、8、9号共有峰数据与Fe3O4相符,3、4号共有峰数据与SiO2相符;通过ICP-MS法确定磁石药材中含有24种元素并测定其含量。其中Fe的含量最高,重金属及有害元素也有检出。FTIR、XRD、ICP-MS可用于磁石的结构鉴定,实验结果为磁石的质量分析奠定了基础。Several methods were employed to explore the composition of Mongolian medicine magnetite.Fourier transform infrared spectroscopy(FTIR)and X-ray diffraction(XRD)were used to determine the spectra of 10 batches of sample from different manufacturers,while elements in magnetite were quantified by inductively coupled plasma mass spectrometry(ICP-MS).Therefore,seven characteristic peaks were found in the infrared spectra for the magnetite,and the characteristic absorption peaks for quartz and Fe3O4 were at 468 cm-1 and 526 cm-1,respectively.Nine characteristic peaks were detected in XRD experiment.The data of peak 5,7,8 and 9 in the spectrum for magnetite were consistent with those of Fe3O4,while the data of the peak 3 and 4 were consistent with those of SiO2.Meanwhile,ICP-MS was used to quantify 24 elements in magnetite.Results showed that the content of Fe was found to be the highest,and other heavy metals and harmful elements were also detected.FTIR,XRD and ICP-MS could be used to identify the structure of magnetite,which lays a foundation for the quality analysis of magnetite.

关 键 词：蒙药 磁石 物质组成 元素含量 指纹图谱 

分 类 号：O657.63[理学—分析化学] R914.1[理学—化学]