2016—2018年乌鲁木齐市汉族男性痛风与代谢综合征的相关性分析  

Correlation analysis of gout and metabolic syndrome in Han males in Urumqi from 2016-2018

作　　者：加娜尔•巴合提江 叶飞 刘璐[1] 蒋靓 王小敏 夏依达•乌斯满江 曙阿克•巴合提 苗蕾[1] Jianaer·Bahetijiang;YE Fei;LIU Lu;JIANG Liang;WANG Xiao-min;Xiayida Wusimanjiang;Shuake·Baheti;MIAO Lei(School of Public Health,Xinjiang Medical University,Urumqi Xinjiang,830011,China)

机构地区：[1]新疆医科大学公共卫生学院,新疆乌鲁木齐830011

出　　处：《职业与健康》2020年第24期3380-3383,共4页Occupation and Health

基　　金：新疆医科大学大学生创新基金(CX2018045);新疆维吾尔自治区普通高校第一批重点专业-预防医学重点专业(新教高[2016]41号);国家自然科学基金(81460153)。

摘　　要：目的探讨新疆乌鲁木齐市汉族男性痛风与代谢综合征的关系,为痛风患者的长期治疗及制定健康计划提供相关依据。方法选取2016—2018年在新疆医科大学第一附属医院、新疆医科大学附属中医医院、新疆维吾尔自治区人民医院痛风临床医学中心3所三级甲等医院就诊的汉族男性痛风患者400例为病例组,400例汉族男性非痛风患者为对照组,采用病例对照的方法对两组人群进行年龄配比,测量血压、身高、体重和生化指标。分析调查对象中痛风与代谢综合征各相关指标相关性及痛风患者中代谢综合征的患病情况。结果800名调查对象平均年龄为(45.45±11.67)岁。痛风组和对照组代谢综合征患病人数分别为13、3人,患病率分别为3.25%和0.75%,差异有统计学意义(P<0.05)。多因素非条件logistic回归分析结果显示,体质指数(BMI)、舒张压、空腹血糖(FBG)和三酰甘油(TG)为痛风发生的危险因素(P<0.01,OR>1)。当BMI≥25.0 kg/m^(2)时,痛风组和对照组患代谢综合征的分别有271、197例,患病率分别为67.75%和49.25%;当高血压时,痛风组和对照组患代谢综合征的分别有43、24例,患病率分别为10.75%和6.00%;FBG升高时,痛风组和对照组代谢综合征患病分别为103、30例,患病率分别为25.75%和7.50%;TG升高时,痛风组和对照组代谢综合征患病分别为203、162例,患病率分别为50.75%和40.50%;两组差异均有统计学意义(均P<0.05)。痛风组代谢综合征的患病率均高于对照组。结论痛风组中代谢综合征的患病率与代谢综合征的各相关指标密切相关,对代谢综合征及各相关指标进行干预可减少痛风的发生。Objective To explore the correlation between gout and metabolic syndrome in Han males in Urumqi of Xinjiang,provide the relevant basis for the long-term treatment and developing the health planning of gout patients.Methods Totally 400 Han male patients with gout,who were treated in three grade-A tertiary hospitals of the First Affiliated Hospital of Xinjiang Medical University,Hospital of Traditional Chinese Medicine Affiliated to Xinjiang Medical University,and Gout Clinical Medical Center of Xinjiang Uygur Autonomous Region People’s Hospital from 2016-2018,were selected as the case group,while 400 Han males without gout were selected as the control group.The age of the two groups was matched by case-control method,and blood pressure,height,weight and biochemical indexes were measured.The correlation between gout and metabolic syndrome indexes in respondents,and prevalence of metabolic syndrome in gout patients were analyzed.Results The average age of 800 subjects was(45.45±11.67)years old.There were 13 and 3 patients with metabolic syndrome in gout group and control group respectively,while the prevalence rate was 3.25%and 0.75%respectively,and the difference was statistically significant(P<0.05).The results of multivariate unconditions logistic regression analysis showed that body mass index(BMI),diastolic blood pressure,fasting blood glucose(FBG)and triglyceride(TG)were the risk factors for gout(P<0.01,OR>1).When BMI was≥25 kg/m^(2),there were 271 and 197 patients with metabolic syndrome in gout group and control group respectively,with the prevalence rate of 67.75%and49.25%respectively.When hypertension occurred,there were 43 and 24 patients with metabolic syndrome in gout group and control group respectively,with the prevalence rate of 10.75%and 6.00%respectively.When fasting blood glucose was elevated,there were 103 and 30 patients with metabolic syndrome in gout group and control group respectively,with the prevalence rate of25.75%and 7.50%respectively.When triglycerides were elevated,there were 203

关 键 词：痛风 代谢综合征 相关性 

分 类 号：R181.38[医药卫生—流行病学]