肠道菌群——运动干预治疗2型糖尿病的新靶点  

Intestinal Flora:A New Target in the Treatment of Type 2 Diabetes by Exercise Intervention

作　　者：赵翠翠 覃飞[2,3] 耿雪 徐旻霄 瞿超艺[2,4] 赵丽娜 赵杰修 ZHAO Cuicui;QIN Fei;GENG Xue;XU Minxiao;QU Chaoyi;ZHAO Lina;ZHAO Jiexiu(School of Sports Science,Qufu Normal University,Qufu 273165,China;China Institute of Sport Science,Beijing 100061 China;School of Sport,Jinan University,Guangzhou 510032,China;Beijing Sport University,Beijing 100084,China;Shanghai University of Sport,Shanghai 200438,Chin)

机构地区：[1]曲阜师范大学体育学院,山东曲阜273165 [2]国家体育总局体育科学研究所,北京100061 [3]暨南大学体育学院,广东广州510032 [4]北京体育大学,北京100084 [5]上海体育学院,上海200438

出　　处：《体育科研》2021年第2期85-91,共7页Sport Science Research

基　　金：国家自然科学基金(11775059);国家体育总局体育科学研究所基本科研业务费资助项目(基本19-22);广东省省级科技计划社会发展领域项(2017A020220010)。

摘　　要：肠道菌群是人体最大的微生态系统,其结构的紊乱是2型糖尿病发生发展的重要原因之一。运动作为一种内稳态刺激因素,可以通过改变宿主肠道菌群的结构多样性,影响物质能量代谢、免疫系统和神经系统等功能,从而达到防治2型糖尿病的作用。因此本文从肠道菌群的角度出发,对运动改善2型糖尿病的实验性研究及潜在机制进行总结归纳,为基于运动干预调控肠道菌群治疗2型糖尿病提供理论依据和参考。Intestinal flora is the largest microecosystem in human body.Its structural disorder is one of the important causes for the occurrence and development of type 2 diabetes.As a homeostasis stimulating factor,exercise can affect the function of material and energy metabolism,immune system and nervous system by changing the structural diversity of the host intestinal flora.In this way,it can prevent and cure type 2 diabetes.Therefore,from the perspective of intestinal flora,this paper summarizes the experimental studies and potential mechanisms of exercise in improving type 2 diabetes.This provides theoretical basis and reference for the treatment of type 2 diabetes through exercise-based intervention and control of intestinal flora.

关 键 词：肠道菌群 运动 2型糖尿病 

分 类 号：G804[文化科学—运动人体科学]