重灸疗法对心脾两虚型慢性疲劳综合征患者临床疗效的研究  

Clinical Effect of Heavy Moxibustion in Treating Chronic Fatigue Syndrome(Deficiency of Heart and Spleen)

作　　者：边红恩[1] 陈团营[1] 单海军[1] BIAN Hong'en;CHEN Tuanying;SHAN Haijun(The Second Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450002,China)

机构地区：[1]河南中医药大学第二附属医院,河南郑州450002

出　　处：《中医药信息》2021年第3期65-68,共4页Information on Traditional Chinese Medicine

基　　金：河南省科技攻关计划项目(0324420083);河南省中医药管理局课题(2018ZY2047);河南省基础与前沿技术研究计划项目(142300410070);河南中医学院科技创新团队支持计划(2010XCXTD11)。

摘　　要：目的:探讨重灸疗法对心脾两虚型慢性疲劳综合征患者的临床疗效。方法:将符合纳入标准的84例心脾两虚型慢性疲劳综合征患者依据计算机产生的随机分配序列分为两组。对照组予以常规治疗(行为心理治疗、运动疗法和盐酸帕罗西汀),观察组予以常规治疗配合重灸疗法。将两组患者治疗前后主症、次症评分和总分变化,临床疗效,治疗前后T细胞免疫指标变化和安全性作为观察指标进行SPSS20.0统计学检验。结果:治疗前两组主症、次症评分和总分,T细胞免疫指标对比差异均无统计学意义(P>0.05);治疗后两组主症、次症评分和总分均较治疗前下降,CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)均较治疗前升高,且治疗后观察组主症、次症评分和总分均低于对照组,观察组CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)均高于对照组,均有统计学意义(P<0.05);治疗后两组CD8^(+)均无显著变化,且观察组与对照组相近,均无统计学意义(P>0.05);两组疗效分布及总有效率均有统计学意义(P<0.05),不良反应发生率无统计学意义(P>0.05)。结论:对心脾两虚型慢性疲劳综合征患者予以重灸疗法可减轻症状,增强疗效,调节T细胞免疫,且不良反应少。Objective:To explore the clinical effect of heavy moxibustion on chronic fatigue syndrome(deficiency of Heart and Spleen).Methods:84 patients with chronic fatigue syndrome(deficiency of Heart and Spleen)were divided into the control group and the observation group according to the random assignment sequence generated by computer.The control group was given routine treatment(behavioral psychotherapy+exercise therapy+Paroxetine Hydrochloride);on which basis,the observation group was also treated with heavy moxibustion.SPSS 20.0 was used to test the scores of main symptoms and secondary symptoms,the total scores,curative effect,T cell immune indexes and safety before and after the treatment in the two groups.Results:There were no statistical differences in the scores of main symptoms,secondary symptoms,the total scores and T cell immune indexes between the two groups before the treatment(P>0.05).After the treatment,the scores of main symptoms,secondary symptoms and the total scores were significantly decreased,and the levels of CD3^(+),CD4^(+)and CD4^(+)/CD8^(+)were significantly increased compared to those before the treatment in the two groups(P<0.05);of which the improvements in the observation group were more significant(P<0.05).In terms of the level of CD8^(+),there was no significant change after the treatment compared to that before the treatment in the two groups,also there was no statistical difference between the two groups after the treatment(P>0.05).The total effective rate was 100%(42/42)in the observation group,which was significantly higher than 83.33%(35/42)in the control group(P<0.05).There was no statistical difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Heavy moxibustion can alleviate symptoms,enhance curative effect and regulate T cell immunity with high safety in the treatment of chronic fatigue syndrome(deficiency of Heart and Spleen).

关 键 词：重灸疗法 慢性疲劳综合征 心脾两虚 T细胞免疫 

分 类 号：R245.8[医药卫生—针灸推拿学]