Optimizing light delivery in scanning photoacoustic imaging for prostate  

作　　者：PENG Dong-qing LIU Zhi-gao XU Hui-zhen ZHU Li-li LI Hui 彭东青;刘志高;徐惠真;朱莉莉;李晖(School of Science,Jimei University,Xiamen 361021,China;Key Laboratory of Optoelectronic Science and Technology for Medicine Ministry of Education of China,Fujian Provincial Key Laboratory of Photonic Technology,College of Photonic and Electronic Engineering,Fujian Normal University,Fuzhou 350007,China)

机构地区：[1]School of Science,Jimei University,Xiamen 361021,China [2]Key Laboratory of Optoelectronic Science and Technology for Medicine Ministry of Education of China,Fujian Provincial Key Laboratory of Photonic Technology,College of Photonic and Electronic Engineering,Fujian Normal University,Fuzhou 350007,China

出　　处：《Optoelectronics Letters》2021年第1期53-58,共6页光电子快报（英文版）

基　　金：This work has been supported by the National Natural Science Foundation of China(No.61675043);the Natural Science Foundation of Fujian Province(No.2018J01416);the Key Laboratory of Opto Electronic Science and Technology for Medicine of Ministry of Education(No.JYG1808);the National Fund Cultivation Plan of Jimei University(No.ZP2020059)。

摘　　要：The purpose of this study was to optimize the light delivery method in a prostate photoacoustic imaging system. A three dimensional(3D) optical model of the human prostate was developed, and the optical energy distribution in the prostate was estimated via three-dimensional Monte Carlo simulation. Then, the feasibility of prostate photoacoustic imaging(PAI) using two endoscopic light delivery methods was studied. Photoacoustic pressure generation and the corresponding photoacoustic images had been obtained and the comparisons were made between each other. Also, the results of cylinder diffusing light source with different lengths were compared. After that, phantom experiment was carried out to validate the simulation results. Our results would be significant in the optimizing photoacoustic imaging system for an accurate diagnosis of prostate cancer.

关 键 词：DIAGNOSIS LIGHT simulation. 

分 类 号：TP391.41[自动化与计算机技术—计算机应用技术] R737.25[自动化与计算机技术—计算机科学与技术]