含肟探针的制备及在有机磷酸酯化合物检测上的应用  

Preparation of Oxime Probes for Sensitive Detection of Organophosphate Compounds

作　　者：何泽祥 向世帅 朱婧[1,3] 黄德顺 杨璐铭[2] 赵鹏翔 HE Zexiang;XIANG Shishuai;ZHU Jing;HUANG Deshun;YANG Luming;ZHAO Pengxiang(Institute of Materials,China Academy of Engineering Physics,Jiangyou 621908,China;National Engineering Research Center of Clean Technology in Leather Industry,Sichuan University,Chengdu 610065,China;Key Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province,Shantou University,Shantou 515063,China)

机构地区：[1]中国工程物理研究院材料研究所,四川江油621908 [2]制革清洁技术国家工程研究中心(四川大学),四川成都610065 [3]广东省有序结构材料的制备与应用重点实验室(汕头大学),广东汕头515063

出　　处：《皮革科学与工程》2021年第2期50-53,73,共5页Leather Science and Engineering

基　　金：四川省科技厅(218JY0287);表面物理与化学实验室科学技术学科发展基金(XKFZ201505);四川省基金项目(2020YFG0014)。

摘　　要：设计并合成了一系列含肟分子作为检测有机磷酸酯类化合物氰基磷酸二乙酯(DECP)的探针。含肟分子可与DECP发生亲核取代反应,产生环化产物或有机磷酸酯类产物,引起荧光信号的“开启”和电化学信号的“降低”,从而实现对DECP的荧光和电化学双通道检测。荧光分光光度法和循环伏安法对DECP的检出限可达10-11 mol/L。A series of oxime molecules were synthesized as probes for the detection of diethyl cyanophosphonate(DECP).The nucleophilic substitution between oximes and DECP could lead to the formation of cyclization products or organophosphorus esters,which further results in the“turn-on”of fluorescent signals and the“turn-down”electrochemical signals by cyclic voltammetry(CV).Thus,the fluorescent and electrochemical dual-channel detection of DECP could be achieved.Results indicate that the detection limit is 10-11mol/L of DECP for both fluorescence spectrophotometry and CV-based methods.

关 键 词：有机磷酸酯 肟探针 荧光法 电化学法 

分 类 号：TS57[轻工技术与工程—皮革化学与工程]