对围生期孕妇采取肺栓塞危险因素筛查的临床意义  

Clinical Significance of Screening for Risk Factors of Pulmonary Embolism in Perinatal Pregnant Women

作　　者：刘媛 韩雪[1] 江铃 徐健[1] 刘春芳[1] LIU Yuan;HAN Xue;JIANG Ling;XU Jian;LIU Chunfang(Department of Respiratory Medicine,Dalian Central Hospital,Dalian 116000,China)

机构地区：[1]大连市中心医院呼吸科,辽宁大连116000

出　　处：《中国医药指南》2021年第5期57-58,共2页Guide of China Medicine

摘　　要：目的探讨对围生期孕妇采取肺栓塞危险因素筛查的临床意义。方法选取2017年1月至2019年1月大连市中心医院呼吸科收治的40例围生期孕妇,随机分为试验组和对照组,每组20例,对照组围生期孕妇不予以特殊筛查和干预措施,试验组围生期孕妇采用Wells、Geneva以及Caprini肺栓塞危险因素评估量表来判定围生期孕妇发生肺栓塞的可能性,并参照相关指南,针对不同肺栓塞的风险评分来对围生期孕妇采取不同预防措施。比较两组围生期孕妇的肺栓塞、深静脉血栓、出血等不良事件发生率,以及流产、早产、胎盘早剥、新生儿畸形以及胎儿宫内窘迫等不良妊娠结局发生率。结果试验组围生期孕妇的肺栓塞、深静脉血栓、出血不良事件发生率显著低于对照组(P<0.05);试验组围生期孕妇发生流产、早产、胎盘早剥以及胎儿宫内窘迫的概率均显著低于对照组(P<0.05)。结论对围生期孕妇采取肺栓塞危险因素筛查的意义重大。Objective To explore the clinical significance of screening risk factors of pulmonary embolism for perinatal pregnant women. Methods A total of 40 perinatal pregnant women from January 2017 to January 2019 in the department of respiratory. Dalian Central Hospital in Liaoning province were randomly divided into the experimental group and the control group, and 20 perinatal pregnant women in the control group were not given screening and intervention measures. In the experimental group of 20 perinatal pregnant women, Wells, Geneva and Caprini pulmonary embolism risk factor assessment scale were used to determine the possibility of PE in perinatal pregnant women, and different prevention measures were taken for perinatal pregnant women according to the risk score of different pulmonary embolism according to relevant guidelines. PE/DVT, adverse bleeding events, incidence of adverse pregnancy outcomes and all-cause mortality in perinatal women were compared between the two groups. Results The incidence of pulmonary embolism, deep vein thrombosis, and bleeding adverse events in the perinatal period of the experimental group was significantly lower than that of the control group(P<0.05), the perinatal period of the experimental group was associated with miscarriage, premature delivery, placental abruption, and fetal distress the probabilities were significantly lower than those of the control group(P<0.05). Conclusion It is of great significance to screen the risk factors of pulmonary embolism for pregnant women during the perinatal period.

关 键 词：肺栓塞 孕妇 围生期 危险因素筛查 妊娠结局 

分 类 号：R563.5[医药卫生—呼吸系统]