Clinical observation of biomimetic mineralized collagen artificial bone putty for bone reconstruction of calcaneus fracture  

作　　者：Yong-Xiong Pan Guang-Gang Yang Zhong-Wan Li Zhong-Min Shi Zhan-Dong Sun 

机构地区：[1]Department of Foot and Ankle Orthopedics,Guangzhou Orthopedic Hospital,Guangzhou 510045,China [2]Department of Foot and Ankle Orthopedics,Shanghai Sixth People’s Hospital,Shanghai 200233,China

出　　处：《Regenerative Biomaterials》2018年第2期61-67,共7页再生生物材料（英文版）

摘　　要：This study investigated clinical outcomes of biomimetic mineralized collagen artificial bone putty for bone reconstruction in the treatment of calcaneus fracture.Sixty cases of calcaneal fractures surgically treated with open reduction and internal fixation in our hospital from June 2014–2015 were chosen and randomly divided into two groups,including 30 cases treated with biomimetic mineralized collagen artificial bone putty as treatment group,and 30 cases treated with autogenous ilia as control group.The average follow-up time was 17.263.0 months.The results showed that the surgery duration and postoperative drainage volume of treatment group were significantly lower than control group;there were no statistically significant differences in the fracture healing time,American Orthopaedic Foot and Ankle Society scores at 3 and 12 months after surgery,Bo¨hler’s angle,Gissane’s angle and height of calcaneus between the two groups.There were no significant differences in wound complication and reject reaction between the two groups,while significant difference in donor site complication.As a conclusion,the implantation of biomimetic mineralized collagen artificial bone putty in the open reduction of calcaneal fracture resulted in reliable effect and less complications,which is suitable for clinical applications in the treatment of bone defect in calcaneal fractures.

关 键 词：calcaneus fracture mineralized collagen artificial bone putty bone substitute bone grafting 

分 类 号：R49[医药卫生—康复医学]