Laryngopharyngeal reflux disease management for recurrent laryngeal contact granuloma:A case report  

作　　者：Kai Li Wen-Yong Chen Yun-Ying Li Tu-Lu Wang Meng-Jia Tan Zong Chen Hai Chen 

机构地区：[1]Department of Otorhinolaryngology,The Second Clinical College of Guangzhou University of Chinese Medicine,Guangzhou 510000,Guangdong Province,China

出　　处：《World Journal of Clinical Cases》2021年第8期1989-1995,共7页世界临床病例杂志

摘　　要：BACKGROUND Laryngeal contact granuloma(LCG)is difficult to treat and frequently associated with high persistence and recurrence,despite the availability of both surgical and pharmacological treatment options.An appropriate strategy is therefore needed to help patients with multiple recurrences of LCG to potentially avoid unnecessary surgery.CASE SUMMARY We describe the case of a 34-year-old male patient with recurrent LCG in which a good response was achieved through successful management of laryngopharyngeal reflux disease using a combination pharmacotherapeutic regimen consisting of anti-reflux therapy,pepsin secretion inhibition,bile acid neutralization,and lifestyle modifications.This patient underwent surgery to excise the granuloma,then relapsed,underwent a second surgery,which was followed by a second recurrence.The granuloma then disappeared after 9 mo of combined treatment with ilaprazole enteric-coated capsules(10 mg qd),mosapride tablets(5 mg tid)and compound digestive enzyme capsules(2 tablets).The drug regimen was discontinued after one year,and no recurrence of the lesion has been reported during the one-year follow-up period.CONCLUSION We report a combination of pharmacotherapeutics and lifestyle modifications for the management of laryngopharyngeal reflux disease to address recurring LCG.

关 键 词：Recurrent laryngeal contact granuloma Laryngopharyngeal reflux disease management Anti-reflux therapy Pepsin secretion inhibition Bile acid neutralization Case report 

分 类 号：R767[医药卫生—耳鼻咽喉科]