肝硬化患者肌肉减少症的评估与干预策略  

Assessment and intervention strategies for sarcopenia in patients with liver cirrhosis

作　　者：肖慧娟 韩涛[1,3,4,5,6] Xiao Huijuan;Han Tao(The Third Central Clinical College of Tianjin Medical University,Tianjin 300170,China;Department of Nutrition,The Third Central Hospital of Tianjin,Tianjin 300170,China;department of Gastroenterology and Hepatology,The Third Central Hospital of Tianjin,Tianjin 300170,China;Tianfin Key Laboratory of Extracorporeal Life Support for Critical Diseases,Tianjin 300170,China;Artificial Cell Engineering Technology Research Center,Tianjin 300170,China;Tianjin Institute of Hepatobiliary Disease,Tianjin 300170,China)

机构地区：[1]天津医科大学三中心临床学院,300170 [2]天津市第三中心医院营养科,300170 [3]天津市第三中心医院肝内科,300170 [4]天津市重症疾病体外生命支持重点实验室,300170 [5]天津市人工细胞工程技术研究中心,300170 [6]天津市肝胆疾病研究所,300170

出　　处：《中华肝脏病杂志》2021年第3期199-203,共5页Chinese Journal of Hepatology

基　　金：国家十三五科技重大专项(2017ZX10203201-007)。

摘　　要：肌肉减少症是肝硬化患者常见的并发症,对患者的临床结局和预后具有不良影响,需要予以足够重视,及早发现,积极诊治。临床上,可遵循发现可疑病例(筛查)-评估-确诊-严重程度评估的诊断流程。针对肝硬化及其并发症治疗基础上,合理的营养干预和运动是目前肝硬化合并肌少症治疗的重要措施,激素补充、针对骨骼肌代谢途径药物治疗的作用尚需要进一步证实。Sarcopenia is a common complication in patients with liver cirrhosis,which has an adverse effect on the clinical outcome and prognosis.Attention must be paid to early detection and active diagnosis and treatment.Clinically,the diagnosis process of finding suspicious cases can be traced through screeningassessment-diagnosis-severity evaluation.On the ground of treating liver cirrhosis and its complications,reasonable nutritional intervention and exercise are currently important measures for the treatment of liver cirrhosis with sarcopenia,and the role of hormone supplementation and drug therapy for skeletal muscle metabolism needs to be further investigated.

关 键 词：肝硬化 肌少症 评估 治疗 策略 

分 类 号：R575.2[医药卫生—消化系统]