全自动化学发光免疫分析仪在梅毒螺旋体抗体检测中效果分析  

Analysis of the Effect of Automatic Chemiluminescence Immunoanalyzer in the Detection of Treponema Pallidum Antibody

作　　者：李欣欣[1] 董淑娟 LI Xin-xin;DONG Shu-juan(Department of Laboratory,Shandong Chest Hospital,Shandong Jinan 250101)

机构地区：[1]山东省胸科医院检验科,山东济南250101

出　　处：《中国医疗器械信息》2021年第6期48-49,167,共3页China Medical Device Information

摘　　要：目的:探讨在对梅毒螺旋抗体的检测中通过应用全自动化学发光免疫分析仪的检测效果。方法:抽取2018年6月~2020年11月本院230例疑似梅毒感染者,均抽取空腹静脉血并分别接受TPPA法检测和CLIA法检测TPsAb,以TPPA法检测结果作为金标准,对比TPPA法、CLIA法在TPsAb中的检测阳性率,并计算CLIA法在TPsAb检测中的准确率、灵敏度以及特异度。结果:230例受试者经TPPA法检测,确诊为TPsAb阳性者共计122例,阳性率为53.04%,CLIA法检测结果显示TPsAb阳性者共计120例,阳性率为52.17%,TPPA法和CLIA法检测的阳性率对比P>0.05;CLIA法诊断的准确率为99.13%,灵敏度为98.36%,以及特异度为100.00%。结论:在梅毒螺旋体抗体检测中通过应用全自动化学发光免疫分析仪的价值较高。Objective:To investigate the effect of automatic chemiluminescence immunoanalyzer in the detection of syphilis helical antibody.Methods:Extract from June 2018 to November 2020 in our hospital 230 cases of suspected syphilis infection,extraction of fasting venous blood and tested for TPPA method respectively and the TPsAb CLIA method and TPPA method in detecting results as the gold standard,compare the TPPA method,CLIA method in the detection rate of positive TPsAb,and calculate the CLIA method in TPsAb detection accuracy,sensitivity and specific degrees.Results:A total of 230 subjects were confirmed to be TPsAb positive by TPPA method,including 122,with a positive rate of 53.04%.The results of CLIA method showed that 120 subjects were TPsAb positive,with a positive rate of 52.17%.The accuracy,sensitivity and specificity of CLIA were 99.13%,98.36%and 100.00%respectively.Conclusion:The application of automatic chemiluminescence immunoanalyzer in the detection of syphilis helicoid antibody is of high value,which can be used as a preferred method for the detection of syphilis helicoid antibody in clinical application and promotion.

关 键 词：梅毒螺旋体抗体 检测 全自动化学发光免疫分析仪 效果 

分 类 号：R446.6[医药卫生—诊断学]