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作 者:王贝贝[1] 阚清[1] 邹芸苏[1] 程锐[1] 周晓光[1] WANG Bei-Bei;KAN Qing;ZOU Yun-Su;CHENG Rui;ZHOU Xiao-Guang(Department of Neonatology,Children's Hospital of Nanjing Medical University,Nanjing 210008,China)
机构地区:[1]南京医科大学附属儿童医院新生儿医疗中心,江苏南京210008
出 处:《中国当代儿科杂志》2021年第3期283-287,共5页Chinese Journal of Contemporary Pediatrics
基 金:南京市卫生科技发展专项资金项目(YKK18142)。
摘 要:3日龄健康足月顺产女婴,Apgar评分:1 min 10分、5 min 10分,生后第3天凌晨母婴同床时突发心跳、呼吸停止,经积极抢救恢复自主呼吸及心跳,复苏时间持续约10 min,复苏后患儿反应差并出现抽搐,血气分析提示代谢性酸中毒,振幅整合脑电图提示爆发-抑制图形,诊断为新生儿生后突发意外衰竭。该患儿经亚低温及对症支持治疗,病情好转。该文首次报道国内1例新生儿生后突发意外衰竭,并对其危险因素、病理生理机制、预防和治疗措施进行总结。A healthy full-term female neonate,aged 3 days and born by vaginal delivery(with a 1-minute Apgar score of 10 and a 5-minute Apgar score of 10),had unexpected cardiac and respiratory arrests in the early morning on day 3 after birth and recovered to spontaneous breathing and heartbeat after a 10-minute resuscitation.The child had poor response and convulsion after resuscitation.Blood gas analysis showed metabolic acidosis,and amplitude-integrated EEG showed a burst-suppression pattern.She was diagnosed with sudden unexpected postnatal collapse but improved after hypothermia and symptomatic/supportive treatment.This article reports the first case of sudden unexpected postnatal collapse in China and summarizes related risk factors,pathophysiological mechanisms,and preventive and treatment measures of this disorder.
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