多参数运动心肺功能测试系统的初步应用  

Preliminary application of multi-parameter cardiopulmonary exercise test system

作　　者：刘杰 叶继伦 文斌 袁懋结 LIU Jie;YE Jilun;WEN Bin;YUAN Maojie(Department of Biomedical Engineering,School of Medicine,Shenzhen University,Shenzhen 518060,China;Guangdong Key Laboratory for Biomedical Signal Measurements and Ultrasound Imaging,Shenzhen 518060,China;Shenzhen Key Laboratory for Biomedical Engineering,Shenzhen 518060,China)

机构地区：[1]深圳大学医学部生物医学工程系,广东深圳518060 [2]广东省生物医学信号检测与超声成像重点实验室,广东深圳518060 [3]深圳市生物医学工程重点实验室,广东深圳518060

出　　处：《中国医学物理学杂志》2021年第3期344-349,共6页Chinese Journal of Medical Physics

基　　金：深圳市产业关键技术研发项目(20190215140144982)。

摘　　要：心肺运动试验(CPET)结合呼吸气体、十二导联心电以及功率踏车技术,实时监测在不同负荷条件下,人体心率、氧耗量和二氧化碳排出量等心肺功能参数的动态变化,从而客观、定量地评价心肺储备功能,为医师诊断、评估心肺功能疾病以及运动耐受力提供相应的临床资料。本系统结合十二导联心电图、呼吸流量、血压、二氧化碳和氧气五大生命体征监测功能,联合计算出静息状态下的静态肺功能参数,如用力肺活量(FVC)、慢肺活量(SVC)和最大通气量(MVV)等,计算出运动情况下的动态心肺功能参数,如每分钟摄氧量(VO_(2))、每分钟二氧化碳排出量(VCO_(2))以及无氧阈(AT)等。通过验证,该系统稳定可靠,参数计算准确,可准确诊断运动不耐受,为评价人体呼吸、循环、代谢等功能提供可靠的参考,具有较好的应用前景。Cardiopulmonary exercise test combines the proportion of breathing gas,12-lead ECG and cycloergometer to monitor the real-time dynamic changes of cardiopulmonary function parameters such as heart rate,oxygen consumption and carbon dioxide output under varying load conditions,so as to objectively and quantitatively evaluate cardiopulmonary reserve,thereby providing corresponding clinical data for physicians to diagnose and evaluate cardiopulmonary diseases and exercise tolerance.Five vital signs,namely 12-lead ECG,respiratory flow,blood pressure,carbon dioxide and oxygen,can be monitored by the system for calculating static lung function parameters at rest,such as forced vital capacity,slow vital capacity and maximum ventilation volume,and calculating dynamic cardiopulmonary function parameters during exercise,such as oxygen uptake per minute,carbon dioxide output per minute and anaerobic threshold.Through verification,the system is proved to be stable and reliable,and the parameter calculation is accurate.The proposed system can be used to accurately diagnose exercise intolerance,providing a reliable reference for evaluating the functions of human breathing,circulation,metabolism,etc.,with a good application prospect.

关 键 词：十二导联心电图 呼吸力学 氧气 二氧化碳 静态肺功能 动态心肺功能 

分 类 号：R318[医药卫生—生物医学工程]