不同门控心肌灌注显像测量左心室功能的准确性研究  

Study on the accuracies of different G-MPI in measuring the function of left ventricle

作　　者：刘秀芹[1] 张毓艺 郭悦[1] 秦嵩[1] 张建飞[1] 陈学涛 姚稚明[1] LIU Xiu-qing;ZHANG Yu-yi;GUO Yue(Department of Nuclear Medicine,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China;不详)

机构地区：[1]北京医院核医学科国家老年医学中心中国医学科学院老年医学研究院,北京100730 [2]北京积水潭医院核医学科,北京100035

出　　处：《中国医学装备》2021年第3期37-40,共4页China Medical Equipment

摘　　要：目的:比较分析8帧和16帧门控心肌灌注显像(GMPI)测量左室功能的准确性。方法:选取在医院就诊的86例拟行GMPI检查的患者,所有患者同时行8帧GMPI和16帧GMPI图像采集和重建处理,比较两者的左心室舒张末期容积(EDV)、收缩末期容积(ESV)、射血分数(EF)、高峰充盈率(PFR)、高峰充盈率时间(TTPF)、1/3最大充盈率(MFR/3)等参数,同时与超声心动图(UCG)检查结果进行比较。结果:8帧和16帧GMPI测量的EDV、ESV、EF、PER及PFR值之间高度相关(r=0.972,r=0.954,r=0.885,r=0.814,r=0.751;P<0.05)。两种帧数GMPI判断PFR正常与否间的符合率为70.9%(Kappa=0.446,P=0.000);以LVEF≥50%为左室收缩功能正常的界值,两种帧数GMPI判断LVEF正常或异常的符合率为70.9%。UCG测量的LVEF值为(64.21±5.74)%,8帧GMPI为(52.15±9.00)%(t=-11.376,P<0.05)。UCG检查LVEF≥50%的65例患者中,8帧GMPI判断LVEF异常的比例为32.3%,显著高于与16帧GMPI(4.6%)(x~2=16.557,P<0.05)。UCG判断左室舒张功能正常的23例中,8帧GMPI和16帧GMPI测量的PFR判断判断为异常的比例分别为60.9%和26.1%(x~2=5.662,P<0.05)。结论:8帧与16帧GMPI测量的左心功能各项结果参数之间具有显著相关性,16帧与8帧相比GMPI测得的左室射血分数及高峰充盈率更准确、更能反映受检者的真实情况。Objective:To compare and analyze the accuracies of 8 frames and 16 frames gated myocardial perfusion imaging(GMPI)in measuring function of left ventricle.Methods:Eighty-six patients who prepared to undergo GMPI in Hospital were selected.And all patients underwent simultaneously image acquisition and reconstruction process by 8 frames GMPI and 16 frames GMPI.A series of parameters included left ventricular end-diastolic volume(EDV),end-systolic volume(ESV),ejection fraction(EF),peak filling rate(PFR),peak filling rate time(TTPF),1/3 of maximum filling rate(MFR/3)of the two methods were compared,and then they were compared with the results of ultrasound cardiogram(UCG).Results:There were high correlation in the EDV,ESV,EF,PER and PFR between 8 frames and 6 frames GMPI(r=0.972,r=0.954,r=0.885,r=0.814,r=0.751,P<0.05).The consistency about whether the PFR was normal between the two kinds of frames GMPI was 70.9%(Kappa=0.446,P=0.000).When LVEF≥50%was used as the threshold value of normally left ventricular systolic function,the coincidence rate of judging the normal or abnormal LVEF between 8 frames GMPI and 16 frames GMPI was 70.9%.The LVEF value that was measured by UCG was(64.21±5.74%),and the LVEF value that was measured by 8 frames GMPI was(52.15±9.00)%,and the difference of that between the two methods was significantly(t=-11.376,P<0.05).In 65 patients whose LVEF values of UCG examination were≥50%,the proportion of abnormal LVEF values that were detected by 8 frames GMPI was 32.3%,which was significantly higher than 4.6%of 16 frames GMPI(χ^(2)=16.557,P<0.05).In the 23 cases with normally left ventricular diastolic function who were judged by UCG,the proportions of abnormal PFR values which were judged by the measurement of 8 frames GMPI and 16 frames GMPI were 60.9%and 26.1%,respectively(χ^(2)=5.662,P<0.017).Conclusion:There are significant correlation in these measured results of left ventricular function between 8 frames GMPI and 16 frames GMPI.Compared with 8 frames GMPI,the LVEF and PFR of 16 frames G

关 键 词：核素 门控心肌灌注断层显像(GMPI) 左心室功能 光子发射型电子计算机断层扫描(SPECT) 

分 类 号：R817.4[医药卫生—影像医学与核医学]