Accelerating degradation rate of pure iron by zinc ion implantation  

作　　者：Tao Huang Yufeng Zheng Yong Han 

机构地区：[1]State Key Laboratory for Turbulence and Complex System and Department of Materials Science and Engineering,College of Engineering,Peking University,Beijing 100871,China [2]State Key Laboratory for Mechanical Behavior of Materials,Xian Jiaotong University,Xian 710049,China

出　　处：《Regenerative Biomaterials》2016年第4期205-215,共11页再生生物材料（英文版）

基　　金：This work was supported by the National Basic Research Program of China(973 Program)(Grant No.2012CB619102);National Science Fund for Distinguished Young Scholars(Grant No.51225101);National Natural Science Foundation of China(Grant No.51431002);the NSFC/RGC Joint Research Scheme under(Grant No.51361165101)in China's Mainland and N_CUHK449/13 in Hong Kong,and Beijing Municipal Science and Technology Project(Z141100002814008).

摘　　要：Pure iron has been considered as a promising candidate for biodegradable implant applications.However,a faster degradation rate of pure iron is needed to meet the clinical requirement.In this work,metal vapor vacuum arc technology was adopted to implant zinc ions into the surface of pure iron.Results showed that the implantation depth of zinc ions was about 60 nm.The degradation rate of pure iron was found to be accelerated after zinc ion implantation.The cytotoxicity tests revealed that the implanted zinc ions brought a slight increase on cytotoxicity of the tested cells.In terms of hemocompatibility,the hemolysis of zinc ion implanted pure iron was lower than 2%.However,zinc ions might induce more adhered and activated platelets on the surface of pure iron.Overall,zinc ion implantation can be a feasible way to accelerate the degradation rate of pure iron for biodegradable applications.

关 键 词：biodegradable metals IRON zinc ion implantation BIOCOMPATIBILITY 

分 类 号：F42[经济管理—产业经济]