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作 者:吴明智[1] 史国兵 徐莉莉[3] 宫建[1] WU Mingzhi;SHI Guobing;XU Lili;GONG Jian(Research Group of Jiian Gong on Pharmacoepidemiology and Clinical Drug Evaluation,Shenyang Pharmaceutical University,Shenyang 110016, China;Liaoning Pharmacological Society,Shenyang 110000, China;967 Hospital of the Joint Logistics Support Force,PLA,Dalian 116021, China)
机构地区:[1]沈阳药科大学药物流行病与临床药物评价课题组,沈阳110016 [2]辽宁省药学会,沈阳110000 [3]中国人民解放军联勤保障部队第967医院,大连116021
出 处:《医药导报》2021年第4期461-466,共6页Herald of Medicine
摘 要:目的揭示药物流行病学在研究热点上的特点和趋势。方法以“药物流行病学”和“Pharmacoepidemiology”为检索词分别检索中国知网(CNKI)和PubMed数据库,利用BICOMB软件统计发文年代、作者分布、来源期刊分布,并利用SPSS软件进行共词聚类分析和建立战略坐标图。结果外文文献明显多于中文文献,国内在药物流行病学研究上还有待进一步的积累。药物流行病学研究的高产作者比较少,尚未形成核心作者群。共词聚类分析以及战略坐标结果显示,国内外在药物流行病学研究的侧重点上,既有共同点,又存在着一定的差异,在研究主题的成熟程度上,国内外的研究也存在着差异,国内研究深入且成熟的仅有“药物警戒与药物不良反应”1个主题。结论目前国内的药物流行病学研究还处于兴起的阶段,在药物流行病学的分支研究中还需要系统性和深入性的研究。Objective To reveal the characteristics and trends of research hotspots in pharmacoepidemiology.Methods Chinese and English terms of Pharmacoepidemiology were used as key words to be searched in CNKI and PubMed.BICOMB software was used to analyze publication years,authors'distribution,and source journals'distribution.SPSS software was used for co-word clustering analysis and establishment of strategic coordinate map.Results The number of foreign literatures was significantly more than Chinese literatures,and the domestic pharmacoepidemiology research needs to be further accumulated.There were few high output authors in pharmacoepidemiology studies,and the core author group has not been formed yet.The results of co-word clustering analysis and strategic coordinates show that there were both similarities and differences in the focus of pharmacoepidemiology research in domestic and abroad.There were also differences in the maturity of research hotspots."Pharmacovigilance and adverse drug reactions"was the only in-depth and mature research theme in China.Conclusion The domestic pharmacoepidemiology research is still in the starting stage,and there is need systematic and further research in the branch of pharmacoepidemiology study.
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