辐照对川芎等中药材有效成分提取的影响  

Effect of Irradiation on Extraction of Active Components from Ligusticum Wallichii and Other Chinese Medicinal Materials

作　　者：张晓彬 倪茂君[1] 王静霞[1] 彭朝荣[1] 陈竹平[1] ZHANG Xiaobin;NI Maojun;WANG Jingxia;PENG Chaorong;CHEN Zhuping(Irradiation Preservation Key Laboratory of Sichuan Province,Sichuan Institute of Atomic Energy,Chengdu 610101,China)

机构地区：[1]四川省原子能研究院辐照保藏四川省重点实验室,成都610101

出　　处：《同位素》2021年第2期111-119,共9页Journal of Isotopes

基　　金：四川省科技计划项目(2019YJ0548,2019YFH0032,2020YJ0222,2020YFH0061,2021YFH0064,2021YFSY0041);四川省重大科技专项项目(2019ZDZX0003)。

摘　　要：以人参、黄连、黄芪、川芎、天麻、丹参为研究对象,通过60 Co-γ及电子加速器分别进行辐照辅助处理,研究辐照对中药材主要成分提取率的影响。采用溶剂法超声提取中药材有效成分,考察辐照对人参皂苷、天麻苷等有效成分含量的影响。高效液相色谱和紫外光谱结果显示,在一定吸收剂量处理下,可提高黄连、黄芪中主要有效成分含量,改变人参中不同皂苷比例,川芎、天麻、丹参等有效成分含量则有所降低。辐照辅助处理有利于提高具有相对稳定结构或不易提取、纤维素含量高的中药材有效成分的提取率,通过研究辐照工艺对六种中药材提取的影响,可为辐照加工技术在中药材提取领域的应用提供参考。Panax ginseng,Coptis chinensis,Astragalus membranaceus,Ligusticum wallichii,Gastrodia elata and Salvia miltiorrhiza were used as the research objects.The effects of irradiation on the extraction rate of the main components of Chinese medicinal materials were studied by 60 Co-γirradiation and electron beam accelerator.Solvent ultrasonography was used to extract the active components of Chinese medicinal materials,the content changes of ginsenoside,gastrodin and other effective components were investigated.High performance liquid chromatography and ultraviolet spectroscopy results showed that the content of main active ingredients in Coptis chinensis and Astragalus membranaceus could be increased,the proportion of different kind of ginsenosides could be changed,and the content of effective ingredients such as Ligusticum wallichii,Gastrodia elata and Salvia miltiorrhiza could be decreased after assisted treatment of certain irradiation dosage.Irradiation-assisted treatment is beneficial to improve the extraction rate of effective components of Chinese medicinal materials with relatively stable structure or high cellulose content,which is not easy to extract.The effect of irradiation on the extraction of six kinds of Chinese medicinal materials was studied in this paper,which provided the research basis for the application of irradiation technology in the extraction of Chinese medicinal materials.

关 键 词：辐照 中药材 提取得率 川芎 

分 类 号：TL99[核科学技术—核技术及应用] TS218[轻工技术与工程—粮食、油脂及植物蛋白工程]