40例中老年新型冠状病毒肺炎的疗效观察  

Effect observation on 40 cases of COVID-19 patients in middle-aged and elderly

作　　者：方勇明 殷思纯 钟剑波 方年新[3] 张平[3] Fang Yongming;Yin Sichun;Fang Nianxin;Zhang Ping;Zhong Jianbo(Department of Internal Medicine,Liaobu Hospital of Dongguan 523400;Department of Infectious Diseases,The Ninth People’s Hospital of Dongguan 523000;Department of Respiratory and Critical Care Medicine,Dongguan people's Hospital 523059)

机构地区：[1]广东省东莞市寮步医院,523400 [2]广东省东莞市第九人民医院,523000 [3]广东省东莞市人民医院,523059

出　　处：《首都食品与医药》2021年第5期32-34,共3页Capital Food Medicine

基　　金：2020年东莞市新型冠状病毒肺炎防疫防治技术研究及推广应急攻关专项项目(项目编号:202071715001120),项目名称:新型冠状病毒肺炎的早期预警评分系统及预后随访的研究。

摘　　要：目的 观察抗病毒、甲强龙、胸腺五肽治疗中老年新冠肺炎的临床疗效,总结诊治经验.方法 选取2020年1月~3月东莞市定点收治医院中老年新冠肺炎患者40例,将其随机分为观察组与对照组,每组各20例患者.对照组给予抗病毒及对症治疗;观察组在对照组治疗基础上加用甲强龙、胸腺五肽等药物治疗,将两组患者治疗10天后的疗效进行对比观察.结果 观察组治疗总有效率明显高于对照组,具有统计学意义(P<0.05);观察组治疗10天后,肺部病灶吸收明显高于对照组,具有统计学意义(P<0.05);两组C反应蛋白、降钙素原、淋巴细胞计数及氧合指数没有明显差异(P>0.05).结论 将抗病毒、甲强龙、胸腺五肽治疗应用于中老年新冠肺炎患者治疗,效果明显,能够有效减少肺部病灶渗出,促进肺部病灶吸收,维持肺泡换气功能,对控制中老年新冠肺炎具有重要意义.Objective To observe the clinical efficacy of antiviral,methylprednisolone and thymopentapeptide in the treatment of middle-aged and elderly patients with CO VID-19,summarize diagnosis and treatment experience.Methods Select 40 cases of middle-aged and elderly patients with COVID-19 in designated hospitals in Dongguan from January to March 2020,and randomly divide the patients into observation group and control group,with 20 patients in each group.Control group received antiviral and symptomatic treatment.The observation group was treated with drugs such as methylprednisolone and thymopentin in addition to the treatment in the control group.Compare and observe the curative effect of the two groups of patients after 10 days of treatment.Resu 11 The total effective rate in the observation group was significantly higher than that in the control group(P<0.05).After 10 days of treatment in the observation group,lung lesion absorption was significantly higher than in the control group(P<0.05).No significant difference in C-reactive protein,procalcitonin,and lymphocyte detection between the two groups(P>0.05).Conclusion Anti viral,methylprednisolone and thymopentapeptide treatment has obvious effects in middle-aged and elderly patients with COVID-19.It can effectively reduce the exudation of lung lesions,promote the absorption of lung lesions,and maintain alveolar ventilation.lt is of great significance for the control of middle-aged and elderly patients with COVID-19.

关 键 词：新冠肺炎 中老年患者 疗效观察 

分 类 号：R563.1[医药卫生—呼吸系统]