睡眠呼吸障碍对妊娠妇女母婴结局影响的研究进展  

Advances in research on the effects of sleep disordered breathing on maternal and fetal outcomes in pregnancy

作　　者：谭慧文 刘奕姝 曾尹 肖莉[2] Tan Huiwen;Liu Yishu;Zeng Yin;Xiao Li(Department of Respiratory and Critical Care Medicine,Shengjing Hospital of China Medical University,Shenyang 110004,China;The Sleep Medicine Center,Shengjing Hospital of China Medical University,Shenyang 110004,China)

机构地区：[1]中国医科大学附属盛京医院呼吸与危重症医学科,沈阳110004 [2]中国医科大学附属盛京医院睡眠医学中心,沈阳110004

出　　处：《国际呼吸杂志》2021年第4期315-320,共6页International Journal of Respiration

基　　金：辽宁省重点研发指导计划项目(2019JH8/10300006)。

摘　　要：阻塞性睡眠呼吸暂停低通气综合征(OSAHS)是最常见的睡眠呼吸障碍疾病,该病主要通过间歇性低氧和睡眠片段化对人体呼吸、循环、代谢等多系统产生损害。妊娠期特有的激素水平和生理状态可能诱发或恶化OSAHS,从而增加孕妇的OSAHS患病率。目前,妊娠期OSAHS对孕妇及胎、婴儿妊娠结局的影响已经成为国内外研究热点,但并没有得出一致的结论。因此,本文就妊娠期OSAHS的现状、OSAHS对母婴结局的影响、相关筛查方法以及治疗方面作一综述,为临床医师诊治妊娠期OSAHS患者提供参考。Obstructive sleep apnea hypopnea syndrome(OSAHS)is the most common sleep breathing disease,which can mainly cause damages to the multiple systems of human body by intermittent hypoxia and sleep fragmentation,such as breathing,circulation,and metabolism.Because the specific hormone level and physiological condition during pregnancy may induce or exacerbate OSAHS,the prevalence of OSAHS in pregnant women has increased.Although the researches on the influence of pregnant OSAHS on maternal,fetal and infant outcomes currently have become a hotspot at home and abroad,there is no unanimous conclusion.Therefore,the current status of pregnant OSAHS,the impact of OSAHS on maternal and infant outcomes,related screening methods and therapy of OSAHS would be all reviewed in this article to provide references for clinicians in diagnosing and treating OSAHS during pregnancy.

关 键 词：睡眠呼吸暂停 阻塞性 母婴结局 妊娠期糖尿病 妊娠期高血压 治疗 

分 类 号：R766[医药卫生—耳鼻咽喉科] R714.25[医药卫生—临床医学]