重复经颅磁刺激治疗慢性前庭综合征疗效评价  

Effect of repetitive transcranial magnetic stimulation on chronic vestibular syndrome

作　　者：李佳威 刘晓阳[1] 杨星昱 孙晓明 李曦丹 LI Jiawei;LIU Xiaoyang;YANG Xingyu;SUN Xiaoming;LI Xidan(Department of Electrophysiology Science,Dalian Third Peoples Hospital,Dalian 116000,Liaoning,China)

机构地区：[1]大连市第三人民医院神经电生理科,辽宁大连116000

出　　处：《山东大学耳鼻喉眼学报》2021年第1期7-10,共4页Journal of Otolaryngology and Ophthalmology of Shandong University

基　　金：辽宁省科学计划指导项目(20180550412)。

摘　　要：目的探讨重复经颅磁刺激(rTMS)治疗慢性前庭综合征(CVS)的疗效。方法慢性前庭综合征(CVS)患者60例,随机数字法分为对照组和治疗组各30例,两组均进行垂直方向和水平方向的平稳跟踪眼动练习,治疗组另加以rTMS治疗4周。以治疗前后两组患者的头晕评价量表(DHI)评分、冷热试验单/双侧半规管反应减退(UW)值为指标,比较分析两组患者治疗前后两项指标的恢复情况。结果治疗前治疗组与对照组DHI评分差异无统计学意义(P=0.872),冷热试验UW值差异无统计学意义(P=0.079),治疗后两组DHI评分减低,差异具有统计学意义(P<0.01),冷热试验UW值减低,差异具有统计学意义(P=0.02),2组治疗前后的DHI评分及UW值差异具有统计学意义(P<0.01),治疗组治疗前后DHI评分差值为39.40分,对照组治疗前后DHI评分差值为25.67分,治疗组治疗前后UW差值为16.03,对照组治疗前后UW差值为12.03。结论rTMS治疗CVS疗效明显,有益于促进前庭代偿建立。Objective This study aimed to investigate the effect of repetitive transcranial magnetic stimulation(rTMS)on chronic vestibular syndrome(CVS).Methods Sixty patients with chronic vestibular syndrome(CVS)were randomly divided into a control group and a treatment group,each with 30 patients.Patients in both groups performed eye-tracking exercises in the vertical and horizontal directions.The treatment group was treated with rTMS for 4 weeks.The dizziness evaluation scale(DHI)score and unilateral/bilateral semicircular canal response(UW)values of the two groups before and after treatment were compared and analyzed.Results There was no significant difference in DHI score between the treatment group and the control group before treatment(P=0.872)while there was no significant difference in UW value between hot and cold test(P=0.079).However,after treatment,the difference of DHI score was statistically significant between the two groups(P<0.01)and the UW value of cold and hot test decreased,and the difference was statistically significant(P=0.02),There were significant differences in DHI score and UW value between the two groups before and after treatment(P<0.01),The difference in DHI score before and after treatment in the treatment group was 39.40 points,while the difference in DHI score before and after treatment in the control group was 25.67 points,the difference in UW score before and after treatment in the treatment group was 16.03,and the difference in UW score before and after treatment in the control group was 12.03.Conclusion rTMS is effective in the treatment of CVS and is good for promoting the establishment of vestibular compensation.

关 键 词：重复经颅磁刺激 前庭综合征 前庭康复 冷热试验 头晕评价量表 

分 类 号：R512[医药卫生—内科学]