益母草与缩宫素联合防治宫缩乏力性产后出血的疗效及安全性分析  

Analysis of the Efficacy and Safety of Motherwort and Oxytocin in the Prevention and Treatment of Postpartum Hemorrhage Caused by Uterine Asthenia

作　　者：李玉莲[1] LI Yu-lian(Department of Obstetrics,Changchun Obstetrics and Gynecology Hospital,Changchun,Jilin Province,130042 China)

机构地区：[1]长春市妇产医院产科,吉林长春130042

出　　处：《中外医疗》2021年第1期106-108,共3页China & Foreign Medical Treatment

摘　　要：目的分析益母草联合缩宫素防治宫缩乏力性产后出血(PPH)的疗效及安全性。方法方便选取2019年3—12月长春市妇产医院收治的98例宫缩乏力性PPH患者分为两组,常规组产妇给予缩宫素治疗,实验组产妇在缩宫素治疗的基础上辅以益母草注射液治疗,比较两组临床疗效、不同时间点的出血量、产后血红蛋白变化及不良反应情况。结果实验组总有效率为95.92%,明显高于常规组的79.59%,差异有统计学意义(χ^(2)=6.078,P<0.05);实验组患者产后2 h、24 h出血量均明显低于常规组,差异有统计学意义(t=7.598、6.469,P<0.05),24 h血红蛋白含量高于常规组,差异有统计学意义(t=7.888,P<0.05);且实验组不良反应发生率为4.08%,常规组为20.41%,两组比较差异有统计学意义(χ^(2)=6.078,P<0.05)。结论对宫缩乏力性PPH患者使用缩宫素联合益母草治疗,能够起到协同增效作用,对减少产后出血量,降低不良反应的发生均有积极的临床价值。Objective To analyze the efficacy and safety of motherwort combined with oxytocin in the prevention and treatment of postpartum hemorrhage due to uterine asthenia(PPH).Methods 98 cases of PPH patients with vterine lock weakness admitted to Changchun Obstetrics and Gynecology Hospital from March to December 2019 were divided into two groups.Pregnant women in the routine group were treated with oxytocin,and pregnant women in the experimental group were treated with oxytocin,with motherwort injection,the clinical efficacy,bleeding volume at different time points,postpartum hemoglobin changes and adverse reactions were compared between the two groups.Results The total effective rate of the experimental group was 95.92%,which was significantly higher than 79.59%of the conventional group,and the difference was statistically significant(χ^(2)=6.078,P<0.05);the blood loss at 2 h and 24 h after delivery of the experimental group was significantly lower than that of the conventional group,and the difference was statistically significant(t=7.598,6.469,P<0.05),the 24 h hemoglobin content was higher than that of the conventional group,and the difference was statistically significant(t=7.888,P<0.05);and the incidence of adverse reactions in the experimental group was 4.08%,and the conventional group was 20.41%.Comparison of the two groups of the difference was statistically significant(χ^(2)=6.078,P<0.05).Conclusion The use of oxytocin combined with motherwort in the treatment of PPH patients with uterine asthenia can have a synergistic effect and have positive clinical value in reducing postpartum hemorrhage and reducing the occurrence of adverse reactions.

关 键 词：产后出血 宫缩乏力 益母草 缩宫素 

分 类 号：R4[医药卫生—临床医学]