老年性糖尿病视网膜病变的用药方案效果分析  

Analysis of the Effect of Medication Regimen for Senile Diabetic Retinopathy

作　　者：刘斌[1] LIU Bin(Department of Ophthalmology,Jilin Provincial People's Hospital,Changchun,Jilin Province,130021 China)

机构地区：[1]吉林省人民医院眼科,吉林长春130021

出　　处：《糖尿病新世界》2021年第2期178-180,共3页Diabetes New World Magazine

摘　　要：目的分析老年性糖尿病视网膜病变的用药方案效果分析。方法现选取2018年6月—2020年6月期间该院眼科收治的96例老年糖尿病视网膜病变患者作为该次研究对象,根据患者的入院时将其分为实验组和对照组,每组均纳入48例,对照组患者在基础治疗之上应用复方樟柳碱注射液治疗,实验组则采用依帕司他联合复方樟柳碱注射液治疗方案,对两组患者的治疗效果和视力恢复情况进行对比和分析。结果实验组治疗前视力(0.33±0.08),治疗后视力(0.72±0.11);对照组治疗前视力(0.34±0.06),治疗后视力(0.64±0.16)。治疗后,两组患者视力均有上升,且实验组患者的视力恢复情况优于对照组,差异有统计学意义(t=2.854,P=0.005);治疗后,实验组患者空腹血糖和餐后2 h血糖水平明显优于对照组,差异有统计学意义(t=5.477、6.928,P<0.001);治疗后,两组患者黄斑中心厚度均有下降,且以实验组患者下降更加明显,差异有统计学意义(t=2.347,P=0.021)。结论在老年性糖尿病视网膜病变的用药方案中,可采用依帕司他联合复方樟柳碱注射液作为主要治疗方案,且可达到良好的应用效果。Objective To analyze the effects of medication regimens for senile diabetic retinopathy.Methods 96 elderly patients with diabetic retinopathy admitted to our hospital's ophthalmology department from June 2018 to June 2020 are now selected as the subjects of this study.According to the patients'admission time,they were divided into experimental and control groups.Enrolled 48 cases,the control group was treated with compound anisodine injection on top of basic treatment,and the experimental group was treated with epalrestat combined with compound anisodine injection.The treatment effect and vision recovery of the two groups of patients were compared and analyzed.Results The visual acuity before treatment in the experimental group was(0.33±0.08)and the visual acuity after treatment(0.72±0.11);the visual acuity before treatment in the control group was(0.34±0.06)and the visual acuity after treatment(0.64±0.16).After treatment,the visual acuity of the two groups of patients increased,and the visual acuity recovery of the experimental group was better than that of the control group,the difference was statistically significant(t=2.854,P=0.005);after treatment,fasting blood glucose and postprandial blood glucose of the experimental group the 2 h blood glucose level was significantly better than that of the control group,and the difference was statistically significant(t=5.477,6.928,P<0.001);after treatment,the macular center thickness of the two groups of patients decreased,and the decrease was more obvious in the experimental group,the difference was statistically significant(t=2.347,P=0.021).Conclusion In the medication regimen for senile diabetic retinopathy,epalrestat combined with compound anisodine injection can be used as the main treatment regimen,which can achieve good application effects and is worthy of application and promotion.

关 键 词：老年性糖尿病 视网膜病变 用药方案 效果分析 

分 类 号：R587.2[医药卫生—内分泌]