前列腺汤口服配合直肠给药治疗慢性前列腺炎血瘀湿热证58例临床观察  

Clinical effect of oral Qianliexian decoction combined with rectal administration in treatment of chronic prostatitis with blood stasis and damp-heat syndrome:An analysis of 58 cases

作　　者：赖聪 柳培兴 张雅 LAI Cong;LIU Peixing;ZHANG Ya(Liuyang Hospital of Traditional Chinese Medicine,Liuyang 410300,Hunan,China;Liuyang Maternal and Child Health Hospital,Liuyang 410300,Hunan,China)

机构地区：[1]浏阳市中医医院,湖南浏阳410300 [2]浏阳市妇幼保健院,湖南浏阳410300

出　　处：《湖南中医杂志》2021年第2期10-13,共4页Hunan Journal of Traditional Chinese Medicine

基　　金：湖南省科技厅临床医疗技术创新引导项目(2018SK51302)。

摘　　要：目的:观察前列腺汤口服配合直肠给药治疗慢性前列腺炎血瘀湿热证的临床疗效。方法:选取慢性前列腺炎血瘀湿热证患者116例,随机分为治疗组和对照组,每组各58例。对照组给予盐酸坦索罗辛缓释胶囊治疗,治疗组在对照组基础上给予前列腺汤口服配合直肠给药治疗。2组均以7 d为1个疗程,连续治疗8个疗程。观察治疗前后中医证候评分、美国国立卫生研究院慢性前列腺炎症状指数(NIH-CPSI)评分及匹兹堡睡眠质量指数量表(PSQI)评分,评价综合疗效。结果:治疗组总有效率为94.83%(55/58)、治愈率为51.72%(30/58),对照组分别为74.14%(43/58)、37.93%(22/58),2组比较,差异均有统计学意义(P<0.05)。2组中医证候、NIH-CPSI及PSQI评分治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P<0.05)。结论:前列腺汤口服配合直肠给药治疗慢性前列腺炎,可改善患者临床症状,提升睡眠质量,提高临床疗效。Objective:To investigate the clinical effect of oral Qianliexian decoction combined with rectal administration in the treatment of chronic prostatitis with blood stasis and damp-heat syndrome.Methods:A total of116 patients with chronic prostatitis with blood stasis and damp-heat syndrome were selected and randomly divided into treatment group and control group,with 58 patients in each group.The patients in the control group were given tamsulosin hydrochloride sustained-release capsules,and those in the treatment group were given oral Qianliexian decoction combined with rectal administration in addition to the treatment in the control group;each course of treatment was 7 days,and both groups were treated for 8 consecutive courses.The two groups were observed in terms of traditional Chines medicine(TCM)syndrome score,National Institutes of Health Chronic Prostatitis Symptom Index(NIH-CPSI)score,and Pittsburgh Sleep Quality Index(PSQI)score before and after treatment,and overall response was evaluated.Results:There were significant differences between the treatment group and the control group in overall response rate[94.83%(55/58)vs 74.14%(43/58),P<0.05]and cure rate[51.72%(30/58)vs37.93%(22/58),P<0.05].Both groups had significant changes in TCM syndrome score,NIH-CPSI score,and PSQI score after treatment,and there were significant differences in these scores between the two groups after treatment(P<0.05).Conclusion:In the treatment of chronic prostatitis,oral Qianliexian decoction combined with rectal administration can improve patients’clinical symptoms,sleep quality,and clinical outcome.

关 键 词：慢性前列腺炎 中西医结合治疗 前列腺汤 盐酸坦素罗辛缓释胶囊 

分 类 号：R277.573.3[医药卫生—中医学]