舒芬太尼用于胸腰椎体手术术后静脉镇痛的剂量分析  

Dosage Analysis of Sufentanil for Postoperative Intravenous Analgesia After Thoracolumbar Vertebra Surgery

作　　者：邵晓勇 SHAO Xiao-yong(Xi'an No.630 Hospital,Xi'an,Shannxi,710089)

机构地区：[1]西安630医院,陕西西安710089

出　　处：《智慧健康》2020年第36期180-181,共2页Smart Healthcare

摘　　要：目的研究分析舒芬太尼在胸腰椎手术术后镇痛的最佳剂量,为后续临床研究提供数据参考。方法以2017年1月至2019年12月在我院接受胸腰椎体手术的88例患者为研究对象,随机分为A、B、C、D四组,以上四组患者使用的舒芬太尼剂量分别为30ug/h、4ug/h、5ug/h、6ug/h;观察四组患者术后镇痛、镇静以及PCA泵有效按压次数。结果 D组患者术后镇痛效果理想于其他三组(P<0.05);四组术后不良反应发生率差异无统计学意义(P>0.05)。结论舒芬太尼用于胸腰椎体手术术后静脉镇痛最佳剂量为6ug/h,该剂量下镇痛镇静效果良好,且未明显增加患者不良反应。Objective To study and analyze the best dose of sufentanil in postoperative analgesia for thoracolumbar surgery,and provide data reference for subsequent clinical research.Methods We chose 88 cases of thoracolumbar vertebra surgery patients in our hospital from January 2017 to December 2019,divided them into four groups randomly:group A,B,C and D.Dosage of sufentanil for above four groups was 30ug/h,4ug/h,5ug/h and 6ug/h respectively;Observe postoperative analgesia,sedation and effective pressing times of PCA pump among four groups.Results Postoperative analgesic effect of group D was better than other three groups (P<0.05);there was no significant difference in incidence of adverse reactions among four groups (P>0.05).Conclusion Optimal dose of sufentanil is 6ug/h for postoperative intravenous analgesia after thoracolumbar vertebra surgery,which has good analgesic and sedative effect,without significant increase of adverse reactions of patients.

关 键 词：胸腰椎体手术 镇静 镇痛 PCA泵 舒芬太尼 

分 类 号：R614[医药卫生—麻醉学]