基于虚毒瘀理论探讨原发性肝癌的治疗  

Discussion on the treatment of primary liver cancer based on the theory of deficiency,toxin and stasis

作　　者：党志博 晏军[3] 李玲孺[4] 李玲[1] 周怡驰 胡世平 DANG Zhibo;YAN Jun;LI Lingru;LI Ling;ZHOU Yichi;HU Shiping(Department of Gastroenterology,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;Department of Hepatology,Shenzhen Hospital,Beijing University of Chinese Medicine,Guangdong Province,Shenzhen 518100,China;Department of Pulmonary Disease,Zaozhuang Hospital,Beijing University of Chinese Medicine,Shandong Province,Zaozhuang 277000,China;Center for Physical and Reproductive Medicine,Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]北京中医药大学东直门医院消化科,北京100700 [2]北京中医药大学深圳医院肝病科,广东深圳518100 [3]北京中医药大学枣庄医院肺病科,山东枣庄277000 [4]北京中医药大学中医体质与生殖医学研究中心,北京100029

出　　处：《中国医药导报》2021年第7期126-129,共4页China Medical Herald

基　　金：国家自然科学基金资助项目(81973733);广东省基础与应用基础研究基金项目(2019A1515011555);广东省深圳市科技计划项目(JCYJ20170306154458909)。

摘　　要：原发性肝癌是临床常见的恶性肿瘤,其发病率及死亡率均较高。中医对于肝功能Child-Pugh B级和C级具有相关治疗适应证的患者可采取辨证施治,可以提高患者生存质量,延长生存期,属于一线治疗策略。从中医角度看,原发性肝癌的病机为正气不足、外邪内侵,致使脏腑功能失调,气血津液代谢失常,日久正气亏虚,痰浊、瘀血、癌毒内生而郁于肝内,则生有形之肿块。其治疗以攻补兼施、扶正祛邪为纲,当从调理肝、脾二脏入手,重视益气化瘀,同时不忘解毒消癥。Primary liver cancer is a common malignant tumor in clinical practice.Its incidence rate and mortality rate are all high.Traditional Chinese medicine for liver function Child-Pugh B and C grade patients with related treatment indications can take the treatment of syndrome differentiation,improve the quality of life of patients,prolong the survival period,whitch belongs to the first-line treatment strategy.From the perspective of traditional Chinese medicine,the pathogenesis of primary liver cancer is deficiency of vital energy and internal invasion of external evils,resulting in dysfunction of viscera function,abnormal metabolism of qi,blood and body fluid,deficiency of vital energy for a long time,phlegm turbidity,blood stasis,cancer toxin endogenous and stagnation in the liver,resulting in tangible masses.The treatment should be based on the treatment of liver and spleen,pay attention to qi and blood stasis,and at the same time,do not forget to detoxify.

关 键 词：健脾益气 化瘀消癥 解毒散结 原发性肝癌 治疗法则 

分 类 号：R273[医药卫生—中西医结合]