痹宁汤联合针刀治疗湿热蕴结型痛风肾关节炎的效果  

Effect of Bining Decoction combined with akupotomye treating gouty nephropathy arthritis with syndrome of accumulation and binding of damp-heat

作　　者：佟颖[1] 胡荣雪 檀佳惠 张淑君[3] 李泽光[1] 张伟平 邵忠林 杨俊朝 TONG Ying;HU Rongxue;TAN Jiahui;ZHANG Shujun;LI Zeguang;ZHANG Weiping;SHAO Zhonglin;YANG Junchao(Department of Rheumatology,the First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Heilongjiang Province,Harbin150040,China;Graduate School,Heilongjiang University of Chinese Medicine,Heilongjiang Province,Harbin150040,China;Department of Pathology,the First Affiliated Hospital of Harbin Medical University,Heilongjiang Province,Harbin150081,China)

机构地区：[1]黑龙江中医药大学附属第一医院风湿科,黑龙江哈尔滨150040 [2]黑龙江中医药大学研究生院,黑龙江哈尔滨150040 [3]哈尔滨医科大学附属第一医院病理科,黑龙江哈尔滨150081

出　　处：《中国医药导报》2021年第9期172-175,共4页China Medical Herald

基　　金：黑龙江省自然科学基金联合引导项目(LH2019 H115)。

摘　　要：目的探讨痹宁汤联合针刀治疗湿热蕴结型痛风肾关节炎(GN)的效果。方法收集2018年12月—2019年12月就诊于黑龙江中医药大学附属第一医院风湿科的符合湿热蕴结型GN诊断的患者60例,采用随机数字表法分将其为治疗组和对照组(每组各30例),治疗组采用痹宁汤联合针刀治疗,对照组采用非布司他片治疗。两组疗程均为7 d。以治疗后两组血尿酸(BUA)、C-反应蛋白(CRP)、24 h尿蛋白定量、视觉模拟评分(VAS)及关节活动积分作为疗效观察指标。结果治疗后,两组BUA、CRP、24 h尿蛋白定量及VAS、关节活动积分均低于治疗前,且治疗组BUA、CRP、24 h尿蛋白定量及VAS、关节活动积分均低于对照组,差异有统计学意义(P<0.05)。结论痹宁汤联合针刀治疗湿热蕴结型GN,可有效降低BUA、CRP、24 h尿蛋白定量,同时能够有效缓解疼痛、改善关节功能。Objective To explore the effect of Bining Decoction combined with akupotomye in the treatment of gouty nephropathy(GN)arthritis with syndrome of accumulation and binding of damp-heat.Methods Sixty patients with GN with syndrome of accumulation and binding of damp-heat admitted to Department of Rheumatology,the First Affiliated Hospital of Heilongjiang University of Chinese Medicine from December 2018 to December 2019 were collected.Through the random number table method,they were divided into treatment group and control group(30 cases in each group).The patients in the treatment group were treated by Bining Decoction combined with akupotomye.The patients in the control group were treated by Febuxostat Tablets.The treatment course for both groups was seven days.After treatment,blood uric acid(BUA),C-reactive protein(CRP),24 h urine protein,visual analog scale(VAS),and joint activity score were used as the indicators of efficacy observation in the two groups.Results After treatment,the quantitative levels of BUA,CRP,24 h urine protein,VAS and joint activity score in both groups were lower than those before the treatment,and the quantitative levels of BUA,CRP,24 h urine protein,VAS and joint activity scores in the treatment group were lower than those in the control group,with statistical significant differences(P<0.05).Conclusion Bining Decoction combined with akupotomye in the treatment of GN with syndrome of accumulation and binding of damp-heat can effectively reduce BUA,CRP 24 h urine protein,relieve pain and improve joint function.

关 键 词：痹宁汤 针刀 湿热蕴结型 痛风肾关节炎 

分 类 号：R589.7[医药卫生—内分泌]