“双通法”内外同治对糖尿病周围神经病变的应用效果观察  

The clinical effects of Shuangtong method internal and external combination treatment in treatment of diabetic perineuropathy

作　　者：魏萱[1] 左建娇[2] 谢秋芳 梁贵廷 王娟[1] 朱玉光 WEI Xuan;ZUO Jianjiao;XIE Qiufang(Department of Endocrinology,TCM Hospital of Shijiazhuang City,Hebei,Shijiazhuang 050000,China)

机构地区：[1]河北省石家庄市中医院内分泌科,050000 [2]河北省石家庄市中医院脾胃科,050000 [3]河北省石家庄市中医院检验科,050000

出　　处：《河北医药》2021年第5期688-692,共5页Hebei Medical Journal

基　　金：河北省中医药管理局科研计划项目(编号:2018224)。

摘　　要：目的研究“双通法”在糖尿病周围神经病变(diabettic periphera neuropathy,DPN)治疗中的应用价值。方法150例糖尿病周围神经病变患者纳入本次研究,患者随机法分为3组,对照组、治疗1组和治疗2组,每组50例。对照组给予神经营养药物甲钴胺治疗;治疗1组在对照组基础上加用阳和汤中药口服治疗;治疗2组在对照组基础上加用双通法(趾尖放血联合阳和汤中药口服)治疗。比较三种不同治疗方案的疗效、症状改善速度及对神经传导速度的影响。结果对照组与治疗1组的疗效及神经传导速度差异无统计学意义(P>0.05),对照组与治疗2组的疗效及神经传导速度差异有统计学意义(P<0.05),治疗1组和治疗2组的疗效及神经传导速度差异有统计学意义(P<0.05)。症状改善速度方面:治疗1个月时:对照组和治疗1组差异无统计学意义(P>0.05);对照组和治疗2组差异有统计学意义(P<0.05);治疗1组和治疗2组差异有统计学意义(P<0.05)。治疗2个月时:对照组和治疗1组差异无统计学意义(P>0.05);对照组和治疗2组比较差异无统计学意义(P>0.05);治疗1组和治疗差异无统计学意义(P>0.05)。治疗3个月时:对照组和治疗1组比较差异无统计学意义(P>0.05)。对照组和治疗2组比较差异有统计学意义(P<0.05)。治疗1组和治疗2组比较差异有统计学意义(P<0.05)。ABI比较方面:治疗前,3组ABI比较均无统计学意义(P>0.05);治疗后,治疗2组ABI均高于治疗1组及对照组,但3组在ABI比较上差异无统计学意义(P>0.05)。结论双通法治疗糖尿病周围神经病变,能显著促进患者神经传导速度的恢复、改善症状,具有见效快、有效率高、效果持续稳定的优势,有助于患者神经病变的恢复和预后的改善。Objective To investigate the clinical effects of Shuangtong method internal and external combination treatment in treatment of diabetic perineuropathy(DPN).Methods A total of 150 patients with DPN who were treated in our hospital were enrolled in the study,who were randomly divided into three gyoups,with 50 cases in each gyoup.The patients in control group were treated by mecobalamin,and the patients in treatment group 1,on the basis of control group,were treated by Yanghe decoction,moreover,the patients n treatment group 2,on the basis of control group,were treated by Shuangtong method(toe bleeding combineded with oral Yanghe decoction).The clinical effects,symptom improvement status and nerve conduction velocity were observed and compared among the three groups.Results There were no significant differences in clinical effects and nerve conduction velocity between treatment group 1 and control group(P>0.05),however,there were significant differences between treatment group 2 and control group and between treatment group 1 and treatment group 2(P<0.05).At 1 month after treatment there was no significant difference in symptom improvement status between treatment group 1 and control group(P>0.05),however,there was significant difference between treatment group 2 and control group and between treatment group 1 and treatment group 2(P<0.05).At 2 months after treatment there was no significant difference between treatment group 1 and control group,between treatment group 2 and control group and between treatment group 1 and treatment group 2(P>0.05).At 3 months after treatment there was no significant difference between treatment group 1 and control group(P>0.05),however,there was significant difference between treatment group 2 and control group and between treatment group 1 and treatment group 2(P<0.05).Before treatment there was no significant difference in ABI among the three groups(P>0.05).After treatment the ABI in treatment groups 2 was higher than that in treatment group 1 and control group.Conclusion The Shua

关 键 词：双通法 内外同治 糖尿病周围神经病变 治疗结果 

分 类 号：R587.1[医药卫生—内分泌]