An unexpected iron(Ⅱ)-promoted reaction of N-arylprop-2-yn-1-imines with water:Facile assembly of multi-substituted pyrroles  

作　　者：Kaida Zhou Jiapian Huang Jie Wu Guanyinsheng Qiu 

机构地区：[1]School of Pharmaceutical and Materials Engineering&Institute for Advanced Studies,Taizhou University,Taizhou 318000,China [2]State Key Laboratory of Organometallic Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032,China [3]College of Biological,Chemical Science and Engineering,Jiaxing University,Jiaxing 314001,China

出　　处：《Chinese Chemical Letters》2021年第1期37-39,共3页中国化学快报（英文版）

基　　金：Financial support from the National Natural Science Foundation of China(Nos.21871053 and 21532001);the Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang(No.2019R01005)is gratefully acknowledged。

摘　　要：Generation of multi-substituted pyrroles is accomplished through an unexpected iron(Ⅱ)-promoted reaction of N-arylprop-2-yn-1-imines with wate r.This transformation proceeds smoothly with excellent chemoselectivityand regioselectivity.A stoichiometric amount of Fe(OTf)_(2) is necessary for the succes s ful conversion.A Lewis acid-promoted tandem reaction pathway is proposed.

关 键 词：Tandem reaction Iron(Ⅱ)triflate Prop-2-yn-1-imine Pyrrole WATER 

分 类 号：TQ251.3[化学工程—有机化工]