Catalyst-and additive-free selective sulfonylation/cyclization of 1,6-enynes with arylazo sulfones leading to sulfonylated γ-butyrolactams  

作　　者：Qishun Liu Yufen Lv Ruisheng Liu Xiaohui Zhao Jiawen Wang Wei Wei 

机构地区：[1]School of Chemistry and Chemical Engineering,Qufu Normal University,Qufu 273165,China [2]Qinghai Provincial Key Laboratory of Tibetan Medicine Research and Key Laboratory of Tibetan Medicine Research,Northwest Institute of Plateau Biology,Chinese Academy of Sciences,Qinghai 810008,China [3]College of Chemistry and Chemical Engineering,Shenyang Normal University,Shenyang 110034,China

出　　处：《Chinese Chemical Letters》2021年第1期136-139,共4页中国化学快报（英文版）

基　　金：supported by the International Cooperation Project of Qinghai Province(No.2018-HZ-806);the Youth Innovation and Technology Project of Higher School in Shandong Province(No.2019KJC021);the Natural Science Foundation of Shandong Province(No.ZR2018MB009);the Qinghai Key Laboratory of Tibetan Medicine Research(No.2017ZJ-Y11);CAS“Light of West China”Program 2018;Entrepreneurship Training Program for College Students(No.201910049)。

摘　　要：A convenient and regioselective sulfonylation/cyclization of 1,6-enynes with arylazo sulfones has been developed to access a series of sulfonylated γ-butyrolactams.The present reaction could be efficiently conducted under catalyst-and additive-free conditions,in which C-S and C-C bonds were selectively constructed in one-pot procedure.

关 键 词：CATALYST-FREE Arylazo sulfones 1 6-Enynes Sulfonylatedγ-butyrolactams 

分 类 号：O624.6[理学—有机化学]