Si-rhodamine based water-soluble fluorescent probe for bioimaging of Cu^(+)  

作　　者：Xiaoyun Chai Weiwei Zhu Qingguo Meng Ting Wang 

机构地区：[1]Department of Organic Chemistry,College of Pharmacy,Second Military Medical University,Shanghai 200433,China [2]College of Pharmacy,Yantai University,Yantai 264005,China

出　　处：《Chinese Chemical Letters》2021年第1期210-213,共4页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(Nos.21602250,81830106);Natural Science Foundation of Shanghai(Nos.19ZR1480000,20ZR1470200).

摘　　要：A Si-substituted rhodamine based water-soluble fluorescent probe bearing a tetrathia-azacrown was designed for fluorescence imaging of Cu^(+) with substantial affinity and selectivity.In physiological condition,the developed probe with outstanding water-solubility exhibits ultrahigh sensitivity to Cu^(+),ensuring the reliable fluorescence imaging in vivo.

关 键 词：Si-rhodamine NEAR-INFRARED WATER-SOLUBILITY Fluorescence imaging Copper 

分 类 号：R318[医药卫生—生物医学工程] O657.3[医药卫生—基础医学]