Mn(Ⅲ)-mediated radical reaction of 2-isocyano-6-alkenyl(alkynyl)benzonitriles with arylboronic acids:Synthesis of pyrroloisoquinoline derivatives  

作　　者：Pei Xu Yi-Ming Zhu Xin-Yu Liu Xiao-Zhou Zhou Shun-Yi Wang Shun-Jun Ji 

机构地区：[1]Key Laboratory of Organic Synthesis of Jiangsu Province,College of Chemistry,Chemical Engineering and Materials Science&Collaborative Innovation Center of Suzhou Nano Science and Technology,Soochow University,Suzhou 215123,China

出　　处：《Chinese Chemical Letters》2021年第1期413-416,共4页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China(Nos.21971174,21772137,21542015 and 21672157);PAPD,the Project of Scientific and Technologic Infrastructure of Suzhou(No.SZS201708);the Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions(No.16KJA150002);Soochow University for financial support。

摘　　要：A Mn(Ⅲ) mediated radical reaction of new designed multi-functionalized 2-isocyano-6-alkenyl(alkynyl)benzonitriles with arylboronic acids has been developed.This reaction provides a method for the synthesis of pyrroloisoquinoline derivatives through the formation of two C-C bonds and one C-N bond via radical cascade cyclization in one step.

关 键 词：2-Isocyano-6-alkenyl(alkynyl)benzonitriles Arylboronic acids Pyrroloisoquinoline derivatives Radical reaction 

分 类 号：O626[理学—有机化学]