Cascade reaction involving intramolecular oxygen-migration:Efficient synthesis of 3-allylidene-indolin-2-one compounds under metal-free conditions  

作　　者：Rui-Ying Zhang Meng-Meng Xu Hai-Yan Li Xiao-Ping Xu Shun-Jun Ji 

机构地区：[1]Key Laboratory of Organic Synthesis of Jiangsu Province,College of Chemistry,Chemical Engineering and Materials Science&Collaborative Innovation Center of Suzhou Nano Science and Technology,Soochow University,Suzhou 215123,China [2]Analysis and Testing Center,Soochow University,Suzhou 215123,China

出　　处：《Chinese Chemical Letters》2021年第1期433-436,共4页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China(Nos.21772138 and 21672157);PAPD,the Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.KYCX19_1899);the Project of Scientific and Technologic Infrastructute of Suzhou(No.SZS201708);State and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials for financial support。

摘　　要：An efficient synthesis of 3-(diarylallylidene)oxindoles from 3-(1 H-indol-3-yl)-1,1-diarylpropan-1-ol under metal-free conditions is described.NBS serves as a critical medium leading to a facile oxygenmigration in the transformation.The protocol has advantages of high efficiency,simple opreation,mild reaction conditions,good atom-economy,wide substrate scope and good yields of products.A detailed mechanism is proposed after careful investigation.

关 键 词：NBS mediated Oxygen migration Conjugate double bonds Multi-step cascade 

分 类 号：O626.13[理学—有机化学]