Role of fibroblast growth factor 23 in patients with chronic kidney disease  

作　　者：Song-Yan Wang Fan Yang Shuang Ma Li-Juan Cui Rui Zhang 

机构地区：[1]Department of Nephrology,Jilin Province People's Hospital,Changchun,Jilin 130021,China

出　　处：《Chinese Medical Journal》2021年第4期404-406,共3页中华医学杂志（英文版）

基　　金：This work was supported by a grant from the Jilin Province Technology and Science Department(No.20200201366JC)。

摘　　要：Fibroblast growth factor 23(FGF23)is a vital osteocyte-derived hormone that regulates the metabolism of phosphorus and 1,25-dihydroxyvitamin D(1,25[OH]2D).1,25(OH)2D and high dietary intake of phosphate up-regulate FGF23 expression,leading to increased renal phosphate excretion and decreased 1,25(OH)2D synthesis,and then suppression of FGF23,thus completing a negative feedback loop.

关 键 词：METABOLISM VITAMIN INTAKE 

分 类 号：R692[医药卫生—泌尿科学]