活血化瘀药治疗高脂血症作用机制实验研究进展  

Experimental research progress of action mechanism of hyperlipoidemia treated by activating blood to resolve stasis medicinals

作　　者：王佐梅 肖洪彬[1] 牛雯颖[1] 李凤金[1] WANG Zuomei;XIAO Hongbin;NIU Wenying;LI Fengjin(Basic Medicine College,Heilongjiang University of Chinese Medicine,Harbin,Heilongjiang,154000,China)

机构地区：[1]黑龙江中医药大学基础医学院,黑龙江哈尔滨154000

出　　处：《甘肃中医药大学学报》2021年第1期97-101,共5页Journal of Gansu University of Chinese Medicine

基　　金：国家自然科学基金青年基金项目(81703981);黑龙江省博士后科研启动基金项目(LBH-Q16213);黑龙江省博士后面上项目(LBHZ18250);黑龙江省普通本科高等学校青年创新人才培养计划项目(UNPYSCT-2018232);黑龙江省高校基金科研业务费支持计划项目(2017PT07);黑龙江省普通本科高等学校青年创新人才培养计划项目(UNPYSCT-2016077)。

摘　　要：从调节血脂水平、对血小板的影响、改善血液流变学及对红细胞膜的影响等四方面概述活血化瘀药对高脂血症的作用,分析其作用机制及相关作用靶点。目前虽然有关活血化瘀药治疗高脂血症的研究较多,但对其作用机制的研究还不够深入。今后应对活血化瘀药治疗高脂血症的作用机制进行深入研究,从而为高脂血症的临床用药提供借鉴。This paper summarizes the effect of activating blood to resolve stasis medicinals on hyperlipoidemia from four aspects,including regulating blood lipid level,affecting platelet,improving hemorheology and affecting erythrocyte membrane,and analyzes its action mechanism.At present,although there are many researches on the treatment of hyperlipoidemia with activating blood to resolve stasis medicinals,the research on its action mechanism is not deep enough.In the future,it is necessary to conduct in-depth study on the action mechanism of activating blood to resolve stasis medicinals in the treatment of hyperlipidemia,thereby providing a reference for clinical medication of hyperlipidemia.

关 键 词：高脂血症 活血化瘀药 血脂水平 血小板 血液流变学 红细胞膜 综述 

分 类 号：R285.5[医药卫生—中药学] R589.2[医药卫生—中医学]