艰难梭菌感染诊断团体标准解读  

Interpretation of group standard for Clostridioides difficile infection diagnosis

作　　者：吴媛[1] 卢金星[1] 闫中强[2] 刘运喜[2] 古文鹏[3] 伏晓庆[3] 徐英春[4] 吴安华[5] 黄海辉[6] 宗志勇[7] 金大智 赵建宏[9] 陈烨[10] 刘卫平 李卫光[12] Wu Yuan;Lu Jinxing;Yan Zhongqiang;Liu Yunxi;Gu Wenpeng;Fu Xiaoqing;Xu Yingchun;Wu Anhua;Huang Haihui;Zong Zhiyong;Jin Dazhi;Zhao Jianhong;Chen Ye;Liu Weiping;Li Weiguang(National Institute for Communicable Disease Control and Prevention,Chines Center for Disease Control and Prevention,Beijing 102206,China;Chinese People's Liberation Army General Hospital,Beijing 100853,China;Yunnan Provincial Center for Disease Control and Prevention,Kunming 650022,China;Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Beijing 100730,China;Xiangya Hospital of Central South University,Changsha 410008,China;Huashan Hospital,Fudan University,Shanghai 200040,China;West China Hospital,Sichuan University,Chengdu 610041,China;Hangzhou Medical College,Hangzhou 310053,China;The Second Hospital of Hebei Medical University,Shijiazhuang 050061,China;Southern Hospital of Southern Medical University,Guangzhou 510515,China;Inner Mongolia Autonomous Region People's Hospital,Hohhot 010017,China;Shandong Provincial Hospital,Ji'nan 250021,China)

机构地区：[1]中国疾病预防控制中心传染病预防控制所,北京102206 [2]中国人民解放军总医院,北京100853 [3]云南省疾病预防控制中心,昆明650022 [4]中国医学科学院北京协和医院,北京100730 [5]中南大学湘雅医院,长沙410008 [6]复旦大学附属华山医院,上海200040 [7]四川大学华西医院,成都610041 [8]杭州医学院,310053 [9]河北医科大学第二医院,石家庄050061 [10]南方医科大学南方医院,广州510515 [11]内蒙古自治区人民医院,呼和浩特010017 [12]山东省立医院,济南250021

出　　处：《中华流行病学杂志》2021年第1期64-67,共4页Chinese Journal of Epidemiology

基　　金：国家科技重大专项(2018ZX10733402)。

摘　　要：艰难梭菌是引起抗生素相关性腹泻和医疗机构相关性腹泻的重要病原,在欧美引起暴发流行,造成沉重疾病负担。然而我国艰难梭菌感染调查缺乏统一的诊断原则和检测技术规范,我国艰难梭菌感染率和疾病负担尚不明确。因此中国CDC传染病预防控制所联合全国其他11家单位撰写《艰难梭菌感染诊断(T/CPMA 008-2020)》中华预防医学会团体标准,以"合法性、科学性、先进性、可行性"为原则,给出了艰难梭菌感染的危险因素、诊断原则、诊断和鉴别诊断。旨在提高临床感染性腹泻中艰难梭菌感染诊断的准确性,指导监测工作开展,明确我国艰难梭菌感染的风险和疾病负担。Clostridioides difficile is a key pathogen of antibiotic related diarrhea and hospital associated infection,causing several outbreaks in Europe and North Americans and resulting in severe disease burden.However,the standardized diagnostic principle and detection specifications in C.difficile infection(CDI)survey are limited in China,and the infection rate and disease burden of CDI in China are unclear.Therefore,National Institute for Communicable Disease Control and Prevention,National Institute for Communicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention,together with another 11 institutions,draft the group standard entitled"Diagnosis of Clostridium difficile infection(T/CPMA 008-2020)"of Chinese Preventive Medicine Association.Based on the principle of"legality,scientificity,advancement,and feasibility",this standard clarifies risk factors,diagnosis principles,diagnoses and differential diagnoses in order to improve the accuracy of CDI diagnosis in clinical practice,guide the surveillance for CDI,and understand the infection rate and disease burden of CDI in China.

关 键 词：艰难梭菌感染 诊断 检测 团体标准 

分 类 号：R516[医药卫生—内科学]