云实属植物化学成分、药理作用及质量控制研究进展  

Chemical constituents,biological activities and quality control of plants from Caesalpinia

作　　者：袁丽 刘慧 黄勇[1] 王爱民[3] 巩仔鹏[1] 李月婷[1] 陈思颖[1] 郑林[1] YUAN Li;LIU Hui;HUANG Yong;WANGAimin;GONG Zipeng;LI Yueting;CHEN Siying;ZHENG Lin(Guizhou Key Laboratory of Pharmaceutical Preparations/State Key Laboratory of Medicinal Plant Efficacy and Utilization,Guizhou Medical University,Guiyang 550004,China;School of Pharmacy,Guizhou Medical University,Guiyang 550004,China;Engineering Research Center for Development and Application of National Medicine and Chinese Medicine of Guizhou Medical University,Guiyang 550004,China)

机构地区：[1]贵州医科大学贵州省药物制剂重点实验室/药用植物功效与利用国家重点实验室,贵州贵阳550004 [2]贵州医科大学药学院,贵州贵阳550004 [3]贵州医科大学民族药与中药开发应用教育部工程研究中心,贵州贵阳550004

出　　处：《药物评价研究》2021年第2期424-431,共8页Drug Evaluation Research

基　　金：国家自然科学基金资助项目(81803842,U1812403);贵州省科技计划项目(黔科合平台人才[2019]5660,[2017]5601);中央引导地方科技专项项目(黔科中引地[2018]4006);贵阳市科研创新团队项目(筑科合同[2017]30-29号)。

摘　　要：云实属Caesalpinia L.植物资源丰富,主要分布在热带和亚热带地区,具有很高的药用价值。目前,已经从云实属植物中分离出的化学成分主要包括黄酮类和萜类两大类,药理研究表明其具有抗炎、抗氧化、抗疟等药理作用。近年来,关于云实属植物的质量控制研究比较单薄,不能全面反映药材质量标准。因此,系统综述了该属植物化学成分、药理作用和质量控制研究进展,以期为云实属植物药用活性成分及其作用机制的研究、资源的充分利用、新药开发提供依据。The plants of Caesalpinia L.are abundant in plant resources,mainly distributed in tropical and subtropical regions.It has extensive medicinal value.At present,the chemical constituents isolated from the Caesalpinia L.mainly include flavonoids and terpenes,which have anti-inflammatory,anti-oxidant,anti-malarial and other pharmacological effects.In recent years,there are few studies on quality control of Caesalpinia L.,which cannot fully reflect the quality of medicinal materials.This research systematically reviews the chemical composition,pharmacological action and quality control of this genus,with a view to providing a basis for the research on the medicinal active ingredients and their mechanism of action,the full utilization and development of resources.

关 键 词：云实属 化学成分 药理作用 质量控制 

分 类 号：R285.5[医药卫生—中药学]