Recent Advances of Trifluoromethoxylation Reactions Using TFMS and TFBO  

作　　者：Xiaohuan Jiang Pingping Tang 

机构地区：[1]State Key Laboratory and Institute of Elemento-Organic Chemistry,College of Chemistry,Nankai University,Tianjin,300071 China

出　　处：《Chinese Journal of Chemistry》2021年第2期255-264,共10页中国化学（英文版）

基　　金：We are deeply indebted to all of the group members.We also thank the National Key Research and Development Program of China(2016YFA0602900);NFSC(21672110,21925105);the Natu-ral Science Foundation of Tianjin(Grant No.18JCIQJC47000);the Fundamental Research Funds for the Central Universities for financial support.

摘　　要：The OCF_(3)group has good metabolic stability,suitable lipophilicity and special electrical properties,which can modify the properties of drugs and material molecules.In recent years,trifluoromethoxy compounds have received more and more attention.Both new reagents and new trifluoromethoxylation strategies got a breakthrough.Our group has been committed to the development of trifluoromethoxylation reagents and methods.This account focuses on describing various trifluoromethoxylation reactions with trifluoromethyl sulfonates(TFMS)and(E)-O-trifluoromethyl-benzaldoximes(TFBO)developed by our group.

关 键 词：Trifluoromethoxylation reagents FLUORINE CARBOCATIONS RADICALS Synthetic methods 

分 类 号：O62[理学—有机化学]